Registration Dossier
Registration Dossier
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EC number: 910-245-3 | CAS number: -
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Additional information
Sodium Hydroxide: Source - the sodium hydroxide summary risk assessment report JRC EC 2008 NaOH did not induce mutagenicity in in vitro and in vivo studies. Systemic carcinogenicity is not expected to occur because NaOH is not expected to be systemically available in the body under normal handling and use conditions. Finally, no suitable studies are available to assess the risk on local carcinogenic effects.
Justification for selection of carcinogenicity via oral route endpoint:
Sodium Hydroxide: Source - the sodium hydroxide summary risk assessment report JRC EC 2008
NaOH did not induce mutagenicity in in vitro and in vivo studies. Systemic carcinogenicity is not expected to occur because NaOH is not expected to be systemically available in the body under normal handling and use conditions. Finally, no suitable studies are available to assess the risk on local carcinogenic effects.
Justification for selection of carcinogenicity via inhalation route endpoint:
Sodium Hydroxide: Source - the sodium hydroxide summary risk assessment report JRC EC 2008
NaOH did not induce mutagenicity in in vitro and in vivo studies. Systemic carcinogenicity is not expected to occur because NaOH is not expected to be systemically available in the body under normal handling and use conditions. Finally, no suitable studies are available to assess the risk on local carcinogenic effects.
Justification for selection of carcinogenicity via dermal route endpoint:
Sodium Hydroxide: Source - the sodium hydroxide summary risk assessment report JRC EC 2008
NaOH did not induce mutagenicity in in vitro and in vivo studies. Systemic carcinogenicity is not expected to occur because NaOH is not expected to be systemically available in the body under normal handling and use conditions. Finally, no suitable studies are available to assess the risk on local carcinogenic effects.
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