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Short-term toxicity to fish

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Description of key information

LC50 (96 h) Zebra fish > 1000 mg/l

Key value for chemical safety assessment

LC50 for freshwater fish:
1 000 mg/L

Additional information

Acute toxicity for Zebra fish was evaluated in the 96 hours screening test, according to the OECD guideline 203. Two concentrations were administrated at 562 and 1000 mg/l with no effect (Ciba - Geigy Ltd., 1992).

The study result is supported by other studies performed between 1973 and 1999 on Zebra fish at 96h for which only a summary is available indicating LC50 all greater than 1000 mg/l.

Furthermore, a prolonged semistatic assay over 14 days was conducted with Brachydanio rerio. Endpoints were mortality, signs of intoxication, length and weight. The nominal concentrations were 100, 316 and 1000 mg/l. There was no mortality and no difference in body weight at nominal concentrations of 100 and 316 mg/l. Only at 316 mg/l one fish showed slackening in movement (Bayer AG., 1992).

Two fish acute toxicity tests are available (Ciba-Geigy, 1994 and 1998) on CAS 16090-02-1 pre-treated with light in order to obtain a high percentage of photodegraded products and verify their impact on aquatic toxicity. Both tests resulted in a LC50 > 100 mg/l, demonstrating that those degradation products are no more dangerous for the environment than the parent compounds.

In conclusion, no fish acute toxicity is expected for CAS 16470-24-9 or its degradation products.