Registration Dossier
Registration Dossier
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EC number: 203-492-7 | CAS number: 107-46-0
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Log Kow (hexamethyldisiloxane): 5.06±0.07 at 20°C (measurement)
Log Koa (hexamethyldisiloxane): 2.74 ±0.05 at 20°C (measurement)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 5.06
- at the temperature of:
- 20 °C
Additional information
A measured log Kow value of 5.06±0.007 at 20°C (5.2 at 25°C, extrapolated) was determined for the substance using an acceptable scientific method but not in compliance with GLP. The result is considered to be reliable and selected as key study. This value is supported by a predicted log Kow of 5.2 at 25°C using a validated QSAR estimation method. In secondary sources to which reliability could not be assigned, a log Kow value of 4.2 was reported for the substance.
Log Koa values of 2.74 at 20°C (water saturated octanol) and 2.96 at 23.7°C (dry octanol) were determined in reliable studies conducted according to scientifically sound methods.
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