Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
additional ecotoxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Non-guideline study addressing non-standard endpoints. Unclear if stoppered containers were used and if nominal concentrations were maintained.

Data source

Reference
Reference Type:
publication
Title:
Cytotoxicity of 109 chemicals to goldfish GFS cells and relationships with 1-octanol/water partition coefficients
Author:
Saito, H., Koyasu, J., Yoshida, K.
Year:
1993
Bibliographic source:
Chemosphere, 1993, 26(5), 1015-1028

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
In vitro cytotoxicity study of goldfish scale cells. Survey of the toxicity of 109 chemicals and their relationship with the logPow. Details on the method published separately (Saito, H., Iwami, S., Shigeoka, T., Chemosphere, 1991, 23, 525-537).
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Diethyl ether
EC Number:
200-467-2
EC Name:
Diethyl ether
Cas Number:
60-29-7
Molecular formula:
C4H10O
IUPAC Name:
diethyl ether

Results and discussion

Any other information on results incl. tables

Midpoint cytotoxicity, 24 hours, NR50=20g/L

Applicant's summary and conclusion