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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable documented study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1982

Materials and methods

Type of study / information:
Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)
Endpoint addressed:
skin irritation / corrosion
Principles of method if other than guideline:
other:Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)

Test material

Constituent 1
Chemical structure
Reference substance name:
Di(benzothiazol-2-yl) disulphide
EC Number:
204-424-9
EC Name:
Di(benzothiazol-2-yl) disulphide
Cas Number:
120-78-5
Molecular formula:
C14H8N2S4
IUPAC Name:
2-(1,3-benzothiazol-2-yldisulfanyl)-1,3-benzothiazole
Details on test material:
SH-82-009, 2,2'-dithio-bis-benzothiazole, test substance 70% in petrolatum

Method

Details on study design:
Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)

Results and discussion

Results:
no primary skin irritating effects observed in 0/53 volunteers

Any other information on results incl. tables

A repeated insult patch test gave no indication of skin irritation after repeated dermal application

Applicant's summary and conclusion