Registration Dossier
Registration Dossier
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EC number: 203-941-7 | CAS number: 112-16-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The reliability of the data is not assignable since the publication is written in Japanese, only abstract, tables and figures were in English. Therefore, no further details could be derived from this test.
Key value for chemical safety assessment
Additional information
Regarding the information requirements of REACH for this tonnage band, a study on the toxicity to microorganisms is not required.
Parent compound lauroyl chloride:
No data are available for lauroyl chloride (CAS 112 -16 -3). The substance rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and lauric acid (CAS 143 -07 -7). Therefore, the toxicity to microorganisms is assessed based on a weight-of evidence approach on the sodium salt of lauric acid (sodium laurate, CAS 629 -25 -4).
Sodium laurate (CAS 629 -25 -4)
The toxicity to microorganisms is assessed via two publications on the biodegradability of sodium laurate. The reliability of the data is not assignable since both publications were written in Japanese, only abstract, tables and figures were in English. Therefore, no further details could be derived.
1) Abe et al., 1984. In two DOC die-away test using river water from two Japanese rivers as inoculum, sodium laurate was assessed to be readily biodegradable (90% in 19 d;10 -d window kept). The test concentration was 20 mg/L.
2) Mihara et al. (1992). In an activated sludge respiration inhibition test, an EC50 of 410 mg/L was determined.
Based on the available data, a NOEC of >= 20 mg/L can be derived. Regarding the low water solubility of lauric acid, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
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