Registration Dossier
Registration Dossier
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EC number: 202-640-8 | CAS number: 98-13-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1969
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The study did not meet current guideline requirements for skin irritation/corrosion. The original report was not available for review.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 969
- Reference Type:
- other company data
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- No data available.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Trichloro(phenyl)silane
- EC Number:
- 202-640-8
- EC Name:
- Trichloro(phenyl)silane
- Cas Number:
- 98-13-5
- Molecular formula:
- C6H5Cl3Si
- IUPAC Name:
- trichloro(phenyl)silane
- Details on test material:
- No data.
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
- Duration of treatment / exposure:
- No data.
- Observation period:
- No data.
- Number of animals:
- No data.
Results and discussion
In vivo
- Other effects:
- Highly corrosive. Causes severe burns.
Applicant's summary and conclusion
- Interpretation of results:
- highly corrosive
- Remarks:
- Migrated information Criteria used for interpretation of results: not specified
- Conclusions:
- The test substance was determined to be highly corrosive in a study which did not meet current guideline requirements for acute dermal toxicity. It does, however, add weight of evidence for trichloro(phenyl)silane toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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