Registration Dossier
Registration Dossier
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EC number: 202-640-8 | CAS number: 98-13-5
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The study did not meet current guideline requirements for acute dermal toxicity. It does however add weight of evidence for trichloro(phenyl)silane toxicity.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 951
- Report date:
- 1951
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Test type:
- standard acute method
Test material
- Reference substance name:
- Trichloro(phenyl)silane
- EC Number:
- 202-640-8
- EC Name:
- Trichloro(phenyl)silane
- Cas Number:
- 98-13-5
- Molecular formula:
- C6H5Cl3Si
- IUPAC Name:
- trichloro(phenyl)silane
- Details on test material:
- No details available.
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No information available
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 0.9 mL/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LD50 value of 0.9 ml/kg was determined in a study which did not meet current guideline requirements for acute dermal toxicity in rabbits. It does, however, add weight of evidence for trichloro(phenyl)silane toxicity.
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