2-chloroaniline

Long-term toxicity to fish

Administrative data

Endpoint:

long-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Only secondary literature

Data source

Reference

Reference 1

Reference Type:

secondary source

Title:

Testing decisions of the TSCA Interagency Testing Committee for Chemicals on the Canadian Environmental Protection Act Domestic Substances List and Priority substances List: Di-tert-butylphenol, Ethyl Benzene, Brominated Flame Retardants..., and Anilines

Author:

Walker JD

Year:

1996

Bibliographic source:

Environmental Toxicology and Risk Assessment: Fourth Volume, ASTM STP 1262, La Point TW et al. (eds.) American Society for Testing and Materials

Reference 2

Reference Type:

other: TSCA ITC Report

Title:

unknown (secondary source (Walker 1996) doesn't state which of the ITC reports in the reference list is the one from which the fish test results were taken)

Author:

TSCA Interagency Testing Committee

Materials and methods

Principles of method if other than guideline:

Only secondary literature available; endpoint study record was created to contribute to the overall results

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

2-chloroaniline

EC Number:

202-426-4

EC Name:

2-chloroaniline

Cas Number:

95-51-2

Molecular formula:

C6H6ClN

IUPAC Name:

2-chloroaniline

Sampling and analysis

Analytical monitoring:

yes

Test organisms

Test organisms (species):

Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Water media type:

freshwater

Total exposure duration:

105 d

Results and discussion

Effect concentrations

Duration:

105 d

Dose descriptor:

other: MATC (maximum acceptable toxicant concentration)

Effect conc.:

0.007 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

test mat.

Any other information on results incl. tables

Only secondary literature available; endpoint study record was created to contribute to the overall results:

The result reported was taken only from a secondary literature source. Taking this into account, the study record currently has to be assessed as not reliable. Unfortunately, the secondary source (Walker 1996) doesn't state which of the ITC reports in the reference list is the one from which the fish test results were taken.

This long-term result of a maximum acceptable toxicant concentration MATC of 0.0067 mg o-chloroaniline/L is about 2 orders of magnitute below the acute fish toxicity values (EC50 and EC0).