Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
fertility, other
Remarks:
based on test type (migrated information)
Type of information:
other: Secondary reference IUCLID4
Adequacy of study:
other information
Reliability:
4 (not assignable)

Data source

Reference
Title:
No information
Author:
Ericsson R.J. und Youngdale G.A.
Year:
1970
Bibliographic source:
J. Reprod. Fert., 21, 263-266

Materials and methods

Principles of method if other than guideline:
Method: other
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloroethanol
EC Number:
203-459-7
EC Name:
2-chloroethanol
Cas Number:
107-07-3
Molecular formula:
C2H5ClO
IUPAC Name:
2-chloroethan-1-ol
Details on test material:
IUCLID4 Test substance: as prescribed by 1.1 - 1.4

Test animals

Species:
rat
Strain:
other: other
Sex:
male

Administration / exposure

Route of administration:
oral: gavage
Duration of treatment / exposure:
Exposure period: 8 Tage
Premating exposure period (males): 8 Tage
Premating exposure period (females): keine
Duration of test: bis zum 10. Tag der Traechtigkeit
Frequency of treatment:
taeglich
Doses / concentrations
Remarks:
Doses / Concentrations:
insgesamt 30 mg/Ratte
Basis:

Control animals:
not specified

Results and discussion

Overall reproductive toxicity

Reproductive effects observed:
not specified

Any other information on results incl. tables

RS-Freetext:
3 maennl. Ratten wurden in den Versuch eingesetzt.
Die Paarung erfolgte einen Tag nach der letzten 
Applikation. Als Parameter fuer die Fertilitaet nahmen die
Autoren die Zahl der Implantationen am 9. bzw. 10. Tag der
Traechtigkeit. Keine Wirkung auf die untersuchten 
Parameter wurde festgestellt. Weitere Angaben liegen nicht
vor.

Applicant's summary and conclusion