Registration Dossier
Registration Dossier
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EC number: 203-091-7 | CAS number: 103-24-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects up to the limit of water solubility (< 0.0004 mg/L in aqua dest) for Pseudokirchneriella subcapitata (OECD 201, limit test)
Key value for chemical safety assessment
Additional information
One study investigating the toxicity of Bis(2 -ethylhexyl) azelate (CAS 103-24-2) to freshwater algae is available. The static study was conducted by a Japanese authority according to GLP and OECD guideline 201 using Pseudokirchneriella subcapitata as test organism (MOE, 2004). A technical product of the substance (77.2% purity) was tested at a nominal test concentration of 0.1 mg/L using HCO-40 as vehicle. The initial test concentration was measured to be 0.0845 mg/L. The concentration after 72 hours was notably lower and not within 20 % of nominal concentration. The EC 50 (72 h) for growth rate is determined to be > 0.0845 mg/L and the NOEC (72 h) for growth rate is determined to be ≥ 0.0845 mg/L on the basis of the initial test concentration, which can be considered as highest achievable test substance concentration using a vehicle under test conditions.
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