Registration Dossier
Registration Dossier
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EC number: 248-258-5 | CAS number: 27138-31-4
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Short description of key information on bioaccumulation potential result:
A study was performed to investigate the metabolism of the14C radiolabelled test substance DEGDB (diethylene glycol dibenzoate CAS no.: 120-55-8) when orally dosed to male and female Sprague Dawley (CD) rats (HLS 2000, VCL 320/993327). The study was conducted to EU and to OECD test guidelines and to GLP. Virtually all of single oral doses of 50 and 750 mg/kg of ring [U-14C phenyl] DEGDB administered to the rats were absorbed metabolised and excreted in the urine within 24 hours of administration. DEGDB was metabolised via hydrolysis of the ester bonds to benzoic acid; this free acid was then conjugated with either glycine (major pathway) or glucuronic acid (minor pathway) prior to excretion.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
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