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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 700-993-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
- Radiolabelling:
- no
- Test temperature:
- In order to ensure a stable performance of the HPLC column, the column temperature was set to 40°C. The reference Koc-values in the OECD guideline presumably refer to 25°C.
- Details on study design: HPLC method:
- HPLC-METHOD PARAMETERS:
- Equipment: HPLC, Agilent 1100
- Column: LiChrospher 100 CN, 250 mm length, 4 mm internal diameter, 5 μm particle size
- Eluent A: 832 ml water + 168 ml buffer pH = 6
- Eluent B: acetonitrile
- Solvent program: Isocratic 80 % A and 20 % B
- Flow: 1 ml/min
- Column temperature:40 °C
- Injection volume: 5 μl
- Detector: UV, 210 nm
PREPARATION OF TEST SOLUTIONS:
Calibration substances and also the solution of sodium nitrate, prepared for the determination of the dead time:
- dissolved in acetonitrile/water 9:1
- concentration of the calibration substances after dilution with acetonitrile to measuring concentration approx. 0.03 to 0.11 mg/ml and 0.10 mg/ml for the solution of sodium nitrate
The test item:
- dissolved in acetonitrile
- concentration of the test item approx. 1.43 mg/ml
pH DETERMINATION OF THE AQUEOUS PART OF THE MOBILE PHASE:
- was done with a pH meter equipped with a calibrated single-rod glass electrode, result: pH 6.3 - Type:
- log Koc
- Value:
- <= -0.7
- Temp.:
- 25 °C
- Remarks on result:
- other: 100 area % of the test item
- Details on results (HPLC method):
- Even though the column temperature was 40°C, this temperature has no influence on the result of the determination. Therefore the Koc -value of the test item determined within this study also refers to 25 °C
- Validity criteria fulfilled:
- not specified
- Conclusions:
- An adsorption coefficient (log Koc) of <= -0.7 was determined at pH 6. The result can be expected to be equal at 25 °C. The value is corresponding to the area weighed logKoc for all peaks of the test item.
- Executive summary:
For the test item the adsorption coefficient was estimated by the HPLC-method according to OECD TG 121. The test was performed at pH 6 (environmental relevant). An adsorption coefficient (log Koc) of <= -0.7 was determined. Even though the column temperature was 40°C, this temperature has no influence on the result of the determination. Therefore the logKoc-value of the test item determined within this study also refers to 25 °C.
Reference
Description of key information
An adsorption coefficient (log Koc) was estimated to be <= -0.7 at pH 6. The value is corresponding to the area weighed logKoc for all peaks of the test item (Garcia-Sanchez, 2012).
Key value for chemical safety assessment
- Koc at 20 °C:
- 0.2
Additional information
Even though the column temperature was 40°C, this temperature has no influence on the result of the determination. Therefore the logKoc-values of the test item determined within this study also refers to 20 °C.
Log KOC = -0.7 may not be entered as Key value. Therefore, -0.7 was calculated as KOC = 0.1995
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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