Registration Dossier
Registration Dossier
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EC number: 214-269-9 | CAS number: 1118-84-9
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- RTECS Number: ES5775000
- Author:
- RTECS database
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances):- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 15,613,1977
- Reference Type:
- review article or handbook
- Title:
- DOSE No.: A77
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE):- Opdyke, D. L. J. Food Cosmet. Toxicol. 1977, 15, 611
- Reference Type:
- review article or handbook
- Title:
- DPIM: AFY250
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials):- Food and Cosmetics Toxicology. 15 (1977), 611.
- Reference Type:
- other: Authoritative data base
- Title:
- GCID: 141749
- Author:
- ACToR Database
- Year:
- 2 011
- Bibliographic source:
- ACToR (Aggregated Computational Toxicology Resource):- Food and Cosmetics Toxicology. Vol. 15, Pg. 613, 1977.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- standard acute method
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Allyl butyrate
- EC Number:
- 218-129-8
- EC Name:
- Allyl butyrate
- Cas Number:
- 2051-78-7
- Molecular formula:
- C7H12O2
- IUPAC Name:
- 2-Propen-1-yl butanoate
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 530 other: mg/kg
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category III
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LD50 value of the substance allyl butyrate wass found to be 530 mg/kg body weight in rabbit.
- Executive summary:
The LD50 value of the substance allyl butyrate is found to be 530 mg/kg body weight in rabbit. This classifies the chemical as being toxic in the toxicity category III as per the CLP criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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