Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information


The ready biodegradability of the Santicizer 278 was determined in a 28 -day biodegradation study performed in accordance with OECD 301B. The test item is considered to be readily biodegradable under the strict terms and conditions of the test.

Water, sediment and soil simulation tests were not required as the substance is readily biodegradable.


The Bioconcentration Factor (BCF) of Santicizer 278 was calculated using the "modified Connell" parabolic equation provided in the R.7c Information Requirements guidelines and using the estimated log Kow of 7.0. A Bioconcentration Factor (BCF) of 45709 l/kg (log BCF of 4.66) was calculated using this equation.

Conduct of additional vertebrate bioaccumulation studies were not required as the substance is readily biodegradable.


The mean estimated log Koc for Santicizer 278 is 5.383.

Additional information