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Diss Factsheets
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EC number: 903-945-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Based on experimental data on each constituent, the reaction mass is considered as toxic to algae.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 7.7 mg/L
- EC10 or NOEC for freshwater algae:
- 0.32 mg/L
Additional information
No data on toxicity to aquatic plants is available on the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA).
The following data are available on each constituent:
For CDFA, in a 72 hour toxicity study (2012), the cultures of Pseudokirchneriella subcapitata were exposed to nominal concentrations of 0.32, 1, 3.2, 10, 32, 100, 316 mg CDFA/L under static conditions in accordance with the OECD Testing Guideline 201 and under GLP conditions. The correct dosing of the test item was performed by using ion chromatography with conductivity detection (IC-CD). During the test the algae were exposed to a mean of 110 % of nominal. Therefore, all reported results refer to nominal concentrations. The results on growth rate were: 72-hour ErC50 = 7.71 mg/L, 72-hour ErC10 = 0.122 mg/L and NOErC = 0.32 mg/L.
For TFA, the GLP compliant OECD 201 study performed by Ineris in 2017 was identified as key study. Green algae (Pseudokirchneriella subcapitata) were exposed during 72h to the test item in static conditions.The initial nominal concentrations were 0.9, 2.5, 7.0, 19.5, 54.7, 153.1, 428.6 and 1200 mg/L (corresponding to the following geometric mean of measured concentration at T0h and at T72h: 0.9, 2.7, 7.2, 20.2, 55.6, 157.6, 438.0 and 1207 mg/L). The test concentrations were analytically monitored by ion-exchange chromatography with gradient elution and conductimetric detection. The test item has been satisfactorily maintained within ± 20 % of the nominal concentration in all test conditions. The endpoint was inhibition of growth, expressed as logarithmic increase of biomass (average specific growth rate) during the exposure period. All validity criteria were fulfilled.In conclusion, the following toxicity values have been determined for the test item trifluoroacetic acid based on nominal concentrations: 72 -hour ErC50 = 237.07 mg/L, 72 -hour ErC10 = 5.59 mg/L and NOErC (72h) = 2.5 mg/L.
Considering that the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA) is mainly composed of CDFA which is the more toxic of the two constituents, the reaction mass is considered as toxic to algae.
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