Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 464-080-2 | CAS number: 613246-79-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to aquatic invertebrates
The acute toxicity of the test substance to Daphnia magna was tested under semi-static conditions according to OECD guideline 202. The EC50 (48 h) was calculated to be 27 mg/L. The NOEC was calculated to be 4.6 mg/L.
Toxicity to aquatic algae and cyanobacteria
The purpose of this study was to determine the effect of the test item SIKA Hardener LTJ (SIKAHärterLTJ) on the growth of a unicellular green algal species Raphidocelis subcapitataaccording to OECD guideline 201. The calculated biological endpoints are EC10 (growth rate) 0.58 mg/L, EC50 (growth rate) 1.70 mg/L, EC10 (yield) 0.27 mg/L, EC50 (yield) 0.70 mg/L, NOEC (growth rate) 0.4 mg/L and NOEC (yield) 0.1 mg/L.
Additional information
Short-term toxicity to aquatic invertebrates
The acute toxicity of the Water Accommodated Fraction (WAF) of Sika Hardener LTJ to Daphnia magna (water flea) was tested under semi-static conditions for 48 hours in accordance with OECD guideline no. 202 and EU method C.2. The test item is immiscible with water and therefore a WAF was prepared. Due to the hydrolysis of SIKA Hardener LTJ no analytical method for the determination of the concentration was available. Thus, the nominal concentrations were used for calculation. The EC50 (48 h) was calculated to be 27 mg/L. The highest concentration causing no immobility (no observed effect concentration, NOEC) after 48 hours amounted to 4.6 mg/L. The EC100 was 100 mg/L, which was observed after 48 hours. All validation criteria were fullfilled.
Toxicity to aquatic algae and cyanobacteria
The purpose of this study was to determine the effect of the test item SIKA Hardener LTJ (SIKA Härter LTJ) on the growth of a unicellular green algal species Raphidocelis subcapitata (formerly known as Pseudokirchneriella subcapitata). Exponentially growing cultures of Raphidocelis subcapitata were exposed to various concentrations of the test item over several generations under defined conditions. The algal growth in relation to a control culture was determined over a fixed test period of 72 hours and thus, over several algal generations. The test method of application and the test species Raphidocelis subcapitata are recommended by the test guidelines. Based on the results of non-GLP Preliminary Range-Finding Test the following six test concentrations in a geometric series (with a spacing factor of 4) were tested: 0.1, 0.4, 1.6, 6.3, 25, 100 mg/L (loading rate). The test concentrations were prepared using the WAF method (by preparing individual WAFs). Due to the rapid hydrolysis of the test item (SIKA Hardener LTJ (SIKA Härter LTJ)) validation of suitable analytical method was not possible for the verification of test item concentration in aqueous test media (Study number 644-100-0646). Analytical determination of the test item concentrations was not feasible, therefore biological endpoints of the test are based on the nominal test item concentrations (loading rate). Biological results are based on the nominal test item concentrations (loading rate).For the determination of the LOEC and NOEC, the calculated mean growth rates and yield at the test concentrations were tested on significant differences to the control values by Bonferroni t-Test using TOXSTAT software. The test item had a statistically significant inhibitory effect on the growth of Raphidocelis subcapitata after the exposure period of 72 hours based on the average specific growth rate in concentrations of 1.6, 6.3, 25 and 100 mg/L and based on yield in concentrations of 0.4, 1.6, 6.3, 25 and 100 mg/L (Bonferroni t-Test, 1 tailed, α=0.05) when compared to control. The ErCx and EyCx values of the test item and their confidence limits were calculated using Probit analysis by TOXSTAT software. The calculated biological endpoints are EC10 (growth rate) 0.58 mg/L, EC50 (growth rate) 1.70 mg/L, EC10 (yield) 0.27 mg/L, EC50 (yield) 0.70 mg/L, NOEC (growth rate) 0.4 mg/L and NOEC (yield) 0.1 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.