Registration Dossier
Registration Dossier
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EC number: 289-550-2 | CAS number: 89923-62-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1986
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: Method B-21
- Deviations:
- not specified
- GLP compliance:
- no
- Specific details on test material used for the study:
- None
- Analytical monitoring:
- no
- Details on sampling:
- None
- Vehicle:
- not specified
- Details on test solutions:
- None
- Test organisms (species):
- activated sludge
- Details on inoculum:
- None
- Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 3 h
- Post exposure observation period:
- None
- Hardness:
- not available
- Test temperature:
- not available
- pH:
- not available
- Dissolved oxygen:
- not available
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- - Nominal concentration of FAT 20242/E: 400, 128, 40 mg/l
- Nominal concentration of the reference substance (3.5-Dichlorophenol): 100, 32, 10 mg/l. - Details on test conditions:
- None
- Reference substance (positive control):
- yes
- Remarks:
- 3.5-Dichlorophenol
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 400 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Details on results:
- None
- Results with reference substance (positive control):
- IC50 (3h) of 3.5-Dichlorophenol was determined to be 19 mg/l.
- Reported statistics and error estimates:
- None
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The IC50 of FAT 20242/E was found to be greater than 400 mg/l.
- Executive summary:
A study was performed on FAT 20242/E to determine the toxicity to microorgsanisms. The inhibitions observed were 1.17, 17.2 and 17.2% at 40, 128 and 400 mg/L, respectively. Based on the findings of the study, the IC50 for FAT 20242/E was found to be greater than 400 mg/L.
Reference
None
Description of key information
The IC50 of FAT 20242/E was found to be greater than 400 mg/l.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 400 mg/L
Additional information
Several studies evaluating toxicity of FAT 20242 to bacteria are available. The IC50 of in these studies was found to be 400 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
