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EC number: 293-106-3 | CAS number: 91051-53-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48h) = 0.074 mg/L (measured, WAF) for Daphnia magna (OECD 202)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.074 mg/L
Additional information
One study investigating the short-term toxicity of the test substance to aquatic invertebrates is available. The test was performed according to GLP and OECD guideline 202 using Daphnia magna as test organism. An EC50 test and and additional limit test were performed based on the result of a preceding range-finding test.Twenty daphnids per test group were exposed to a control and glass fiber filtered solutions prepared at loading rates of 2.2, 4.6, 10, 22, 46 and 100 mg/L in the EC50 test and to a control and a glass fiber filtered solution prepared at a loading rate of 100 mg/L in the additional limit test. Samples for confirmation of actual exposure concentrations were taken at the start and the end of the test period.
A floating layer was formed in all test solutions prepared at a loading rate of 4.6 mg/L and higher. In addition, daphnids were observed trapped at the surface in filtered solutions of 22 mg/L and higher. In order to distinguish between toxic and physical effects, an additional limit test was performed using a physical barrier in the form of a net in the test vessels.
Analysis of the samples taken from the glass fiber filtered solution at the start of the additional limit test showed a measured concentration of 2.0 mg/L.This concentration decreased to 0.62 mg/L at the end of the test. The corresponding average exposure concentration was calculated to be 1.1mg/L and was comparable to the average concentration calculated for the100 mg/L loading rate of the EC50 test. No floating layer was observed in the limit concentration and no daphnids were observed to be trapped at the surface during the test period. However, the number of daphnids immobilized was comparable to the EC50 test. Therefore, immobilisation could be related to toxicity of the test substance rather than a physical effect. The 48h-EC50 was estimated to be between the concentrations present in glass fiber filtered solutions prepared at loading rates of 10 and 22 mg/L. The corresponding average exposure concentration is 0.074 mg/L. Based on this result, the test substance is considered to be very toxic to aquatic invertebrates.
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