Registration Dossier
Registration Dossier
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EC number: 201-265-7 | CAS number: 80-26-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
A GLP-compliant OECD Guideline 301F study (Manometric Respirometry) is available for alpha-Terpinyl Acetate. The test substance was incubated for 28 days with activated sludge from a biological waste water treatment plant treating predominantly domestic sewage as the inoculum. The degradation of the test material was assessed by the oxygen consumption. The test substance biodegrades for 63% after 28 days, under the conditions of the test. Biodegradations starts on day 2 and reaches 58% at the end of the 10-day window. At the concentration tested (100 mg/L), it is not inhibitory to micro-organisms.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
In the ready biodegradability test the biodegradation exceeds 60% but the 10-day window is missed at a few %. According to CLP Annex I section 4.1.2.9.5. and OECD guidance for the testing of chemicals; Section 3 introduction (2006), if the substance is a UVCBs or a complex multi-constituent with structurally similar constituents, and it is anticipated that a sequential biodegradation of the individual structures is taking place, then the 10-day window should not be applied to interpret the results of the test. It is considered that, though alpha-Terpinyl Acetate is a mono-constituent according to ECHA criteria, it consists for 13% of structural homologues of the main constituent for which indeed sequential biodegradation may be anticipated to occur. Based on all available information, the 10-day window condition is waived and the pass level applied at >60% biodegradation within 28 days and therefore alpha-Terpinyl Acetate is qualified as readily biodegradable.
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