Choline chloride

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

GLP compliance:

no

Type of method:

differential scanning calorimetry

Melting / freezing pt.:

> 250 °C

Atm. press.:

1 013 hPa

Decomposition:

yes

Decomp. temp.:

> 300 °C

No unambiguous melting temperature was found up to 200°C, even when there is an endothermic peak at 68 to 80°C (Test 2). The existence of a crystallisation peak during the cooling and the nearly identical endothermic peak in the following heating run might be taken as a proof for the melting of the sample. But the optical check of the samples after the heating and cooling cycles did not show any indication for a flow of the granules.

 

This is in accordance with the measurement in a capillary tube in a metal block, an also applicable method to determine the melting temperature according OECD 102.

This test was performed at GMC/V, where no melting point was found up to 250°C (see section 2.2).:

"The capillary was inserted at a temperature of +50°C, heating rate: 25°C/min up to +250°C. The test item was analyzed twice.

No melting point was observed (Melting point > +250°C) "

 

Also an additional test in a test tube with a hot air blower showed no melting of the test item up to its decomposition (change to brown colour) after a long heating at higher temperature. With these additional observations, the endothermic curve was interpreted as a melting in, but not as the melting of the sample.

"To survey the thermic behaviour of the test item a preliminary TG/DTA-Test (non-ISO 9001) was run up to 700°C. An endothermic peak starting at about 300°C with the weight loss up to about 85% shows the vaporization / decomposition of the test item."

Conclusions:

No unambiguous melting temperature was found up to 200°C via DSC, in addition no melting point found up to 250 °C via capillary tube method. From 300 °C decomposition is observed.

Executive summary:

The melting point of the substance was assessed in a non-GLP study according to OECD guideline 102 via differential scanning calometry and with the capillary tube method.

No unambiguous melting temperature was found up to 200°C via DSC, in addition no melting point found up to 250 °C via capillary tube method. From 300 °C decomposition is observed.

Description of key information

The melting point of the substance was assessed in a non-GLP study according to OECD guideline 102 via differential scanning calometry and with the capillary tube method.

No unambiguous melting temperature was found up to 200 °C via DSC, in addition no melting point found up to 250 °C via capillary tube method. From 300 °C decomposition is observed.

Additional information

A supporting study was performed on the substance contaminated with beet pulp equivalent to OECD Guideline 102 using differential thermal analysis (BASF, 1983). The first signs of an exothermal reaction were denoted at ca. 110 °C, whereas the maximum of this reaction was ca. 200 °C. An additional exothermic reaction took place at about 250 °C with a maximum at 300 °C. This study supports the fact, that the substance decomposes at higher temperatures.