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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Title:
Unnamed
Year:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Annex V
GLP compliance:
yes
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
482-200-1
EC Name:
-
Cas Number:
1184-10-7
Molecular formula:
C36H30N3O6P3
IUPAC Name:
hexaphenoxy-1,3,5,2λ⁵,4λ⁵,6λ⁵-triazatriphosphinine
Test material form:
solid

Test animals

Species:
other: rat(wistar)

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
other: Olive oil
Duration of exposure:
24h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
other: Signs of toxicity related to dose levels: No signs of systemic toxicity observed.
Gross pathology:
Effects on organs:
There were no macroscopic abnormalities observed at time of
autopsy.
Other findings:
Signs of toxicity (local):
No clinical signs were evident in any animal over the
test/observation period.
Erythema were present in all animals on days 2 through 4.
One animal (female) exhibited Erythema on days 2 through 6
and crusts on days 4 through 12.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met