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EC number: 695-101-5 | CAS number: 1275611-65-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13-04-2016 - 12-05-2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD 301D study conducted under GLP conditions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- yes
- Remarks:
- Ammonium chloride was omitted from the medium to prevent oxygen consumption due to nitrification. River water instead of an effluent/extract/mixture was used as inoculum.
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: River Water
- Details on inoculum:
- River water was sampled from the Rhine near Heveadorp, The Netherlands (07-04-2016). The nearest plant (Arnhem-Zuid) treating domestic wastewater biologically was 3 km upstream. The river water was aerated for 7 days before use to reduce the endogenous respiration. River water without particles was used as inoculum. The particles were removed by sedimentation after 1 day while moderately aerating.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 2 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- The Closed Bottle test was performed according to the study plan. The study plan was developed from ISO Test Guidelines (1994). Use was made of 10 bottles containing only river water, 10 bottles containing only river water with test substance 6 bottles containing river water and sodium acetate, 6 bottles containing river water, sodium acetate and test substance. The concentrations of the test substance, and sodium acetate in the bottles were 2.0 and 6.7 mg/L, respectively. Each of the prepared solutions was dispensed into the respective group of BOD bottles so that all bottles were completely filled without air bubbles. The zero time bottles were immediately analyzed for dissolved oxygen using an oxygen electrode. The remaining bottles were closed and incubated in the dark. Two duplicate bottles of all series were withdrawn for analyses of the dissolved oxygen concentration at day 7, 14, 21, and 28.
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 73
- Sampling time:
- 28 d
- Details on results:
- N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine was biodegraded by 73% at day 28 in the Closed Bottle test. Poor water solubility of organic compounds affects the biodegradation kinetics because of slow desorption and dissolution rates of the test substance present at high concentrations. The biodegradation curves of poorly-water soluble substances are linear instead of the anticipated S-shape. It should be noted that under environmental conditions N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine will be present in the environment at very low concentrations. The poor water solubility of N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine is therefore the reason for not applying the time window as pass/fail criterion (Battersby, 2000; Richterich and Steber, 2001). Hence N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine should therefore be classified as readily biodegradable.
- Results with reference substance:
- The biodegradation percentage of the reference compound, sodium acetate, at day 14 was 78%.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- A valid study performed acccording to the guidelines with only a minor deviations;
a) ammonium chloride was omitted from the medium to prevent oxygen consumption due to nitrification (omission does not result in nitrogen limitation as shown by the biodegradation of the reference compound), and b) river water instead of an effluent/extract/mixture was used as inoculum. - Executive summary:
N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine was biodegraded by 73% at day 28 in the Closed Bottle test. Poor water solubility of organic compounds affects the biodegradation kinetics because of slow desorption and dissolution rates of the test substance present at high concentrations. The biodegradation curves of poorly-water soluble substances are linear instead of the anticipated S-shape. It should be noted that under environmental conditions N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine will be present in the environment at very low concentrations. The poor water solubility of N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine is therefore the reason for not applying the time window as pass/fail criterion (Battersby, 2000; Richterich and Steber, 2001). Hence N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine should therefore be classified as readily biodegradable.
Reference
Description of key information
One OECD 301D study has been performed under GLP conditions. The substance was degraded to 73% at day 28 and is therefore readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
One OECD 301D test was performed under GLP conditions. N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine (CAS no 1275611-65-8) was biodegraded by 73% at day 28 in the Closed Bottle test. Poor water solubility of organic compounds affects the biodegradation kinetics because of slow desorption and dissolution rates of the test substance present at relatively high concentrations. The biodegradation curves of poorly-water soluble substances are linear instead of the anticipated S-shape. It should be noted that under environmental conditions N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine will be present in the environment at very low concentrations. The poor water solubility of N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine and the fact that the substance is a UVCB are the reasons for not applying the time window as pass/fail criterion (Battersby, 2000; Richterich and Steber, 2001). Hence N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine should therefore be classified as readily biodegradable.
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