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EC number: 821-762-8 | CAS number: 4563-56-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 03 Jun - 22 Sep 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- adopted in 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- adopted in 2008
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Ministerium für Arbeit, Integration und Soziales des Landes Nordrhein-Westfalen, Düsseldorf, Germany
- Type of method:
- flask method
- Specific details on test material used for the study:
- Storage conditions: at room temperature; tightly closed; dry
- Water solubility:
- ca. 0.16 g/L
- Conc. based on:
- element
- Remarks:
- based on phosphorus analysis
- Temp.:
- 23 °C
- pH:
- ca. 5.75
- Water solubility:
- ca. 0.14 g/L
- Conc. based on:
- element
- Remarks:
- based on sulphur analysis
- Temp.:
- 23 °C
- pH:
- ca. 5.75
- Water solubility:
- ca. 0.072 g/L
- Conc. based on:
- element
- Remarks:
- based on zinc analysis
- Temp.:
- 23 °C
- pH:
- ca. 5.75
Reference
Results
Table 1 – P analysis results
Test item amount [g] |
Added water volume [mL] |
Shaking time at 30 °C [h] |
Dilution factor |
Analysed concentration of P [mg/L] |
Mean value P [g/L] |
pH value* |
0.5193 |
50 |
72 |
10 |
0.941953 |
0.0097 |
5.7 |
0.5052 |
0.999222 |
|||||
0.5134 |
96 |
1.04534 |
0.0106 |
5.8 |
||
0.5163 |
1.06825 |
|||||
0.5078 |
120 |
1.00299 |
0.0103 |
5.7 |
||
0.5085 |
1.06618 |
*the purified water used for the tests had a pH of 5.5
Table 2 – S analysis results
Test item amount [g] |
Added water volume [mL] |
Shaking time at 30 °C [h] |
Dilution factor |
Analysed concentration of S [mg/L] |
Mean value S [g/L] |
pH value* |
0.5193 |
50 |
72 |
10 |
1.64325 |
0.0171 |
5.7 |
0.5052 |
1.77907 |
|||||
0.5134 |
96 |
1.81947 |
0.0184 |
5.8 |
||
0.5163 |
1.86057 |
|||||
0.5078 |
120 |
1.73066 |
0.0179 |
5.7 |
||
0.5085 |
1.84641 |
*the purified water used for the tests had a pH of 5.5
Table 3 – Zn analysis results
Test item amount [g] |
Added water volume [mL] |
Shaking time at 30 °C [h] |
Dilution factor |
Analysed concentration of Zn [mg/L] |
Mean value Zn [g/L] |
pH value* |
0.5193 |
50 |
72 |
10 |
0.478315 |
0.0048*** |
5.7 |
0.5052 |
(0.318900)** |
|||||
0.5134 |
96 |
0.442524 |
0.0047 |
5.8 |
||
0.5163 |
0.495109 |
|||||
0.5078 |
120 |
0.475980 |
0.0048 |
5.7 |
||
0.5085 |
0.489457 |
*the purified water used for the tests had a pH of 5.5
**outlier, not used for test evaluation
***calculated from single measurement
The mean value of the samples after 120 h did not exceed the mean values of the samples (P, S and Zn) after 96 h and 72 h by more than 15%. So, 3 duplicate sets of samples showed no tendency of increasing concentration values.
Table 4 – Results summary (23 °C, pH 5.7 – 5.8)
Water solubility mean value [g/L] |
Standard deviation [g/L] |
Rel. standard deviation [%] |
Water solubility mean value test item [g/L] |
P samples 1 -6: 1.0E-02 |
4.9E-04 |
4.8 |
0.16* |
S samples 1 -6: 1.8E-02 |
8.2E-04 |
4.6 |
0.14** |
Zn samples 1; 3 – 6: 4.8E-03 |
2.0E-04 |
4.3 |
7.2E-02*** |
*Calculated with the content of the neat test item given by the
study monitor: 6.19%
** Calculated with the content of the neat test item given by the study
monitor: 12.90%
*** Calculated with the content of the neat test item given by the study
monitor: 6.69%
The relative standard deviations did not exceed 15%, therefore the tests were valid.
Description of key information
0.16 g/L at 23°C and pH 5.75, based on phosphorus
0.14 g/L at 23 °C and pH 5.75, based on sulphur
0.072 g/L at 23 °C and pH 5.75 based on zinc (OECD 105, Flask method with modified procedure)
Key value for chemical safety assessment
- Water solubility:
- 150 mg/L
- at the temperature of:
- 23 °C
Additional information
The key value of water solubility used for the PNEC and DNEL calculation, as well as in the exposure assessment is the mean value (150 mg/L) of solubility measured based on phosphorus and sulphur, because it is the worst case.
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