Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 230-053-7 | CAS number: 6928-85-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Appearance:
Based on available data from reliable sources such as authoritative database and safety data sheet the chemical 4-methylpiperazin-1-amine was observed to be an organic colourless liquid in appearance.
Freezing point:
Based on the prediction done using the EPI Suite MPVPBP V1.43,the freezing point of chemical4-methylpiperazin-1-aminewas predicted.
The freezing point of chemical4-methylpiperazin-1-aminewas estimated to be 21.57 ˚C
Boiling point:
Based on available data from reliable sources such as authoritative database and safety data sheet the boiling point of chemical 4-methylpiperazin-1-amine was determined to be in the range of 172-175°C at 760 torr.
Density:
Based on available data from reliable handbook the density of chemical 4-methylpiperazin-1-amine was determined to be 0.964 g/cm3 at 25 degree C.
Particle size distribution:
The study does not need to be conducted because the substance is marketed or used in a non solid or granular form.
Vapour pressure:
Modified Grain method (Mean of Antoine and Modified Grain methods) was used to estimate the vapour pressure of the chemical 4-methylpiperazin-1-amine using MPBPVP v1.43 of EPI SUITE.
The estimated vapour pressure of the chemical 4-methylpiperazin-1-amine at 25deg C was 129 Pa.
Partition coefficient:
The Octanol water Partition coefficient (Log Pow) of 4-methylpiperazin1-amine( CAS no. 6928 -85 -4) predicted from EPI Suite and Danish QSAR is -1.61. This value suggests that this chemical is hydrophilic in nature.
Surface tension:
Based on prediction done using ACD labs, surface tension for chemical 4-methylpiperazin-1-amine was predicted to be 35.2 ± 3.0 dyne/cm.
Flash point:
Based on available data from reliable safety data sheet ,the flash point of chemical 4-methylpiperazin-1-amine was determined to be 63 degree C by closed cup menthod.
Auto-flammability:
4-methylpiperazin-1-amine did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 4-methylpiperazin-1-amine is not auto-flammable.
Flammability:
4-methylpiperazin-1-amine does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-methylpiperazin-1-amine is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-methylpiperazin-1-amine was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
Additional information
Appearance:
Based on available data from reliable sources such as authoritative database and safety data sheet the chemical 4-methylpiperazin-1-amine was observed to be an organic colourless liquid in appearance.
Freezing point:
Based on the prediction done using the EPI Suite MPVPBP V1.43,the freezing point of chemical 4-methylpiperazin-1-amine was predicted.
The freezing point of chemical4-methylpiperazin-1-aminewas estimated to be 21.57 ˚C
Boiling point:
Based on available data from reliable sources such as authoritative database and safety data sheet the boiling point of chemical 4-methylpiperazin-1-amine was determined to be in the range of 172-175°C at 760 torr.
Other supporting study based on the prediction done using the EPI Suite MPVPBP V1.43,the Boiling point of chemical4-methylpiperazin-1-aminewas predicted.
The boiling point of chemical4-methylpiperazin-1-aminewas estimated to be 179.90˚C
Density:
Based on available data from reliable handbook the density of chemical 4-methylpiperazin-1-amine was determined to be 0.964 g/cm3 at 25 degree C.
Other supporting study from reliable safety data sheet also indicates that the density of chemical 4-methylpiperazin-1-amine was determined to be 0.957 g/cm3 at 25 degree C
Particle size distribution:
The study does not need to be conducted because the substance is marketed or used in a non solid or granular form.
Vapour pressure:
Modified Grain method (Mean of Antoine and Modified Grain methods) was used to estimate the vapour pressure of the chemical 4-methylpiperazin-1-amine using MPBPVP v1.43 of EPI SUITE.
The estimated vapour pressure of the chemical 4-methylpiperazin-1-amine at 25deg C was 129 Pa.
Surface tension:
Based on prediction done using ACD labs, surface tension for chemical 4-methylpiperazin-1-amine was predicted to be 35.2 ± 3.0 dyne/cm.
Flash point:
Based on available data from reliable safety data sheet ,the flash point of chemical 4-methylpiperazin-1-amine was determined to be 63 degree C by closed cup menthod.
Other supporting study from reliable safety data sheet also indicates that the flash point of chemical 4-methylpiperazin-1-amine was determined to be 62 degree C.
Auto-flammability:
4-methylpiperazin-1-amine did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 4-methylpiperazin-1-amine is not auto-flammable.
Flammability:
4-methylpiperazin-1-amine does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-methylpiperazin-1-amine is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-methylpiperazin-1-amine was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.