Registration Dossier
Registration Dossier
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EC number: 200-877-1 | CAS number: 75-54-7
Endpoint summary
Administrative data
Description of key information
Additional information
No data are available for the toxicity of dichloro(methyl)silane to fish, invertebrates or algae. Reliable acute aquatic toxicity tests results are however available from a read-across substance (Dimethylsilanediol; CAS No. 1066-42-8) for freshwater fish (Oncorhynchus mykiss), invertebrates (Daphnia magna) and algae (Pseudokirchnerella subcapitata). LC50 or EC50 values for the three organisms were >126, >119 and >118 mg/L respectively. A NOEC of ≥118 mg/L was determined in the algal test.
Testing for long-term toxicity to fish and invertebrates is waived in accordance with Column 2 of REACH Annex IX as the chemical safety assessment indicates that it is not necessary:
- Acute toxicity is low.
- The substance is used under highly controlled conditions and, therefore, exposure of the aquatic environment is low (see Section 9 for further details.
- The risk characterisation ratio (RCR) based on PNECaquaticderived from the acute data are <1 (see Section 10 for further details).
An EC50 of 160 mg/l and a NOEC of 32 mg/l for toxicity to microorganisms were determined in a reliable study conducted according to an appropriate test protocol, and in compliance with GLP. It is likely that the inhibition was influenced by the low pH levels at the higher loading rates, but the pH at the NOEC was 7, and therefore the NOEC is considered the most useful and representative result.
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