Registration Dossier
Registration Dossier
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EC number: 202-710-8 | CAS number: 98-88-4
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1974-04 to 1974-06
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The authors followed a methodology similar to the OECD guideline 301D. GLP standards are not specified and some details on methodology are missing. However, basic data are provided, therefore this study should be considered a Klimisch 2e: study well documented, meets generally accepted scientific principles, acceptable for assessment.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 1974
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Benzoyl chloride
- EC Number:
- 202-710-8
- EC Name:
- Benzoyl chloride
- Cas Number:
- 98-88-4
- Molecular formula:
- C7H5ClO
- IUPAC Name:
- benzoyl chloride
- Details on test material:
- - Name of test material (as cited in study report): benzoylchlorid
No more data available
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic (adaptation not specified)
- Details on inoculum:
- No data available
- Duration of test (contact time):
- 20 d
Initial test substance concentration
- Initial conc.:
- 2.4 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- pH: 2.1
No more data available
Results and discussion
- Preliminary study:
- No data available
- Test performance:
- No data available
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 74
- Sampling time:
- 5 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 93
- Sampling time:
- 10 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 95
- Sampling time:
- 20 d
BOD5 / COD results
BOD5 / CODopen allclose all
- Parameter:
- COD
- Value:
- 1 750 other: mg/L
- Parameter:
- BOD5
- Value:
- 1 290 other: mg/L
- Parameter:
- BOD5*100/COD
- Value:
- 74
- Results with reference substance:
- No data available
Any other information on results incl. tables
Table: Overview of the data, extrapolated from BOD and COD supplied
| pH | COD | BOD5 | BOD5/COD | BOD10 | BOD10/COD | BOD20 | BOD20/COD | |
| Benzoyl chloride | 2.1 | 1750 | 1290 | 74% | 1630 | 93% | 1670 | 95% |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The authors tested the biodegradability of benzoyl chloride with a methodology similar to the OECD guideline 301D. In the test conditions, benzoyl chloride was degraded about 74 %, 93 % and 95 % after five, ten and twenty days of incubation respectively. Thus, benzoyl chloride should be considered as readily biodegradable in the test conditions.
- Executive summary:
The authors tested the biodegradability of benzoyl chloride (CAS n° 98 -88 -4) with a methodology similar to the OECD guideline 301D. Few details are available on the materials and methods. In the test conditions, after 5, 10 and 20 days of incubation, benzoyl chloride at 2.4 mg/L was degraded about 74 %, 93 % and 95 %. Thus, the results indicate that the test substance benzoyl chloride should be considered as readily biodegradable in the environment according to EC regulation 1272/2008 and the former 67/548/EC regulation.
No data was available on the GLP status of the study. Besides, the limited amount of available information does not allow to verify the fulfillment of validity criteria. However, since the study was conducted with an accepted test method and that basic data are provided, it should be considered as reliable with restictions, and the document considered as acceptable for assessment.
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