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EC number: 235-741-0 | CAS number: 12645-31-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 23 May 2011 and 23 June 2011.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: Testing was conducted using a procedure designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2208 of 30 May 2008, and Method 104 specified in the OECD Guidelines for Testing of Chemicals, 23 March 2006.
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Temp.:
- 25 °C
- Vapour pressure:
- 0.085 Pa
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure of the test item has been determined to be 8.5 x 10-2 Pa at 25ºC.
- Executive summary:
Method
The vapour pressure was determined using a vapour pressure balance with measurents being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using a procedure designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2208 of 30 May 2008, and Method 104 specified in the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Summary of results
Run
Log10[Vp(25ºC)]
Vapour Pressure at 25°C (Pa)
1
-1.069
8.5 x 10-2
2
-1.109
7.8 x 10-2
3
-1.139
7.3 x 10-2
4
-1.172
6.7 x 10-2
5
-1.193
6.4x 10-2
6
-1.191
6.4 x 10-2
7
-1.216
6.1 x 10-2
8
-1.251
5.6 x 10-2
9
-1.270
5.4 x 10-2
10
-1.281
5.2 x 10-2
Conclusion
The vapour pressure of the test item has been determined to be 8.5 x 10-2 Pa at 25ºC.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study according to OECD guideline 104
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: The calculated vapor pressure is extrapolated
- Temp.:
- 25
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: The calculated vapor pressure is extrapolated
- Temp.:
- 50 °C
- Vapour pressure:
- 0.002 Pa
- Conclusions:
- The vapor pressure measured according to the OECD Guideline 104 for this substance is 0.00012 Pa at 20 °C
- Executive summary:
The vapor pressure measured according to the OECD Guideline 104 for this substance is 0.00012 Pa at 20 °C
Referenceopen allclose all
Summary of Results
Run | Log10[Vp(25ºC)] | Vapour Pressure at 25°C (Pa) |
1 | -1.069 | 8.5 x 10-2 |
2 | -1.109 | 7.8 x 10-2 |
3 | -1.139 | 7.3 x 10-2 |
4 | -1.172 | 6.7 x 10-2 |
5 | -1.193 | 6.4x 10-2 |
6 | -1.191 | 6.4 x 10-2 |
7 | -1.216 | 6.1 x 10-2 |
8 | -1.251 | 5.6 x 10-2 |
9 | -1.270 | 5.4 x 10-2 |
10 | -1.281 | 5.2 x 10-2 |
The test item did not change in appearance under the conditions used in the determination.
Please see Attachment 2 for Graphs of Log10 vapour pressure vs Reciprocal Temp runs 1 -10 and Results tables in Attached background material section.
Thermal Stability
A DSC-measurement in closed glass crucible showed no thermal effects up to 200 °C
Vapour Pressure Balance (Effusion Method)
The vapour pressure was measured in the temperature range of 18 °C to 127 °C Above 62 °C a vapour pressure could be measured. The measured vapour pressures at the corresponding temperatures are listed in the following table:
Temperature/°C | Vapour pressure/hPa |
62.0 | 4.1x10 -5 |
67.0 | 1.5x10 -4 |
70.2 | 1.8x10 -4 |
74.2 | 5.8x10 -4 |
78.3 | 1.8x10 -4 |
82.5 | 5.4x10 -4 |
87.3 | 6.1x10 -4 |
92.8 | 4.3x10 -4 |
98.2 | 9.2x10 -4 |
103.4 | 1.2x10 -3 |
109.4 | 2.1x10-3 |
115.0 | 2.6x10-3 |
121.0 | 6.3x10-3 |
As the test item is a mixture a mean molecular weight was assumed according to the composition given in the certificate of analysis for calculating the vapour pressure by the Knudsen-Hertz formula.
Description of key information
Vapour pressure = 0.085 Pa (25°C); Tremain & Atwal (2011); E.U. Method A.4.
Vapour pressure = 0.00012 Pa (20°C); Dornhagen (2011); OECD 104 (vapour pressure curve)
Key value for chemical safety assessment
- Vapour pressure:
- 0.085 Pa
- at the temperature of:
- 25 °C
Additional information
The overall endpoint determination of vapour pressure was conducted using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using a procedure designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2208 of 30 May 2008, and Method 104 specified in the OECD Guidelines for Testing of Chemicals, 23 March 2006.
A slight, but gradual drop in vapour pressure was observed on repeated temperature cycling of the test item over the range 20 to 30°C (under vacuum), with individual vapour pressure values in the range 8.5 x 10-2 to 5.2 x 10-2 Pa at 25°C for ten consecutive runs. Such vapour pressure characteristics, are indicative of the gradual reduction of a more volatile fraction of the test item.
To provide representative data for risk assessment on accidental release of the test item, the initial, highest value obtained has been taken as the definitive result since although the drift in observed vapour pressure was not significant, such characteristics prevented reporting of a definitive, mean value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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