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Diss Factsheets
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EC number: 203-093-8 | CAS number: 103-26-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Valid acute toxicity tests with the test substance are available for three freshwater species from three trophic levels. The studies show that fish are the most sensitive species with a LC50 = 2.76 mg/L (geom. mean LC0/LC100 of measured concentrations).
In the static guideline study over 96 hours oily droplets were observed at the surface of solution at all concentrations. The concentrations in test medium significantly decreased over study duration. Therefore, the biological results were based on the arithmetic mean of measured concentrations.
In a semi-static daphnia study over 48 hours an EC50 of 24 mg/L was determined. In the valid static algae study the ErC50 after 72 hours was 7.6 mg/L based on geometric mean measured concentration. The ErC10 was determined to be 4 mg/L.
The lowest L(E)C50 value of the three studies (Fish LC50 = 2.76 mg/L) is used in the hazard assessment and for derivation of aquatic PNECs.
A valid test on the toxicity to microorganisms according to ISO 8192 is available. Methyl cinnamate was shown to inhibit the growth of sludge bacteria and an EC50(3h) = 181 mg/L was determined.
No long-term tests on aquatic toxicity are available, but as the risk assessment based on acute toxicity data demonstrated that there is no risk for the aquatic environment, there is no need to investigate further the effects on aquatic organisms.
Although the substance is considered toxic to aquatic organisms according to GHS (Acute 2), classification according to CLP is not required as methyl cinnamate is readily biodegradable (100% biodegradation in 28 days) and has low potential for bioaccumulation (logPOW 2.86).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.