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EC number: 251-257-2 | CAS number: 32846-21-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening tests
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: In house guideline compatable to internationally accepted guidelines
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 5 d
- Test performance:
- None
- Remarks on result:
- not measured/tested
- Parameter:
- BOD5
- Value:
- 0 mg O2/g test mat.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The Biological Oxygen Demand of FAT 20003/H was determined to be 0 mg O2/g test mat.
- Executive summary:
The Biological Oxygen Demand of FAT 20003/H was determined to be 0 mg O2/g test mat.
- Endpoint:
- biodegradation in water: screening tests
- Remarks:
- COD determination
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38409-H41-1.
- Deviations:
- not specified
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Not applicable
- Remarks on result:
- not measured/tested
- Parameter:
- COD
- Value:
- 572 mg O2/g test mat.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The Chemical Oxygen Demand of FAT 20003/H was determined to be 572 mg O2/g test mat.
- Executive summary:
The Chemical Oxygen Demand of FAT 20003/H was determined to be 572 mg O2/g test mat.
- Endpoint:
- biodegradation in water: screening tests
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 12 November, 1997 to 04 February, 1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Code no.: FAT 20003/I
Batch no.: Vers. Nr. 9-5-97
Purity: ca. 90 %
Appearance: red powder
Solubility: 30 g/L
Storage: room temperature
Expiration date: 02/2001 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Activated sludge of a communal sewage treatment plant (ARA Pro Rheno Basel) collected on January 06, 1998 was washed twice with tap water one day before the test was started.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 51 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Performance of the test:
A mixture of a total test volume of 2 L each containing test substance, mineral medium and activated sludge was agitated and aerated at 20-25 °C in two glass vessels for 28 d. A reference control running in duplicate containing activated sludge, mineral medium and the reference substance, and a blank control containing activated sludge and mineral medium were run under the same test conditions. The biodegradation process was monitored by determination of the dissolved organic carbon concentrations (DOC). The ratio of eliminated DOC, corrected for the blank after each time interval, to the initial DOC value was expressed as the percentage biodegradation at each sampling time. The concentration of dissolved oxygen was checked at regular intervals to ensure that the oxygen did not fall below 2 mg/L. The pH was checked and adjusted to pH 7 - 8 if necessary.
Experimental conditions:
Temperature: 20.0 - 22.3 °C
pH: 7.0 - 7.3
O2: 7.2-8.6 mg/L
Sludge dry weight: 0.20 g/L
DOC of distilled water: 0 mg/L
DOC content of test substance: 47.3 %
Amount of test substance (conc.): 106 mg/L
Test volume: 2 L
Test duration: 28 d
Aeration: Continuously aerated by passing fritted glass
Agitation: Continuously stirred with a magnetic stirrer
Lighting: Diffuse daylight - Reference substance:
- diethylene glycol
- Preliminary study:
- no data
- Test performance:
- no data
- Parameter:
- % degradation (DOC removal)
- Value:
- 16
- Sampling time:
- 28 d
- Details on results:
- Adsorption of the test substance after 3 h: 1 %
Biodegradation of the test substance after 28 d: 16 %
Total elimination (regarding adsorption and biodegradation) of the test substance after 28 d: 17 % - Results with reference substance:
- The reference substance was removed by more than 70 % in the first 14 d.
- Validity criteria fulfilled:
- yes
- Remarks:
- (reference substance was removed by more than 70 % in the first 14 d)
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- The test substance is not considered to be inherently biodegradable.
- Executive summary:
An inherent biodegradability study was conducted with the test substance according to OECD Guideline 302 B and EU Method C.4-C in compliance with GLP.
Mixtures of a total volume of 2 L containing test substance, mineral medium and activated sludge were agitated and aerated at 20 - 25 °C in two glass vessels for 28 d. A reference control running in duplicate containing activated sludge, mineral medium and the reference substance, and a blank control containing activated sludge and mineral medium were run under the same conditions. The biodégradation process was monitored by determination of the dissolved organic carbon concentrations (DOC). The ratio of eliminated DOC, corrected for the blank after each time interval, to the initial DOC value was expressed as the percentage biodégradation at each sampling time.
The following result were obtained:
Adsorption of the test substance after 3 h: 1 %
Biodegradation of the test substance after 28 d: 16 %
Total elimination (regarding adsorption and biodegradation) of the test substance after 28 d: 17 %
Based on the above findings, it was concluded that under the study conditions, the test substance was inherently biodegradable.
Referenceopen allclose all
Table 1: Tables of details:
|
DOC concentration (mg/L) |
Biodegradation (%) |
|||||
Time |
Reference mean |
Blank |
Substance 1 |
Substance 2 |
Reference mean |
Substance 1 |
Substance 2 |
Start |
51 |
- |
51 |
51 |
- |
- |
- |
3h |
52 |
2 |
53 |
52 |
- |
- |
- |
Day 1 |
56 |
7 |
53 |
52 |
2.0 |
9.8 |
10.0 |
Day 7 |
48 |
7 |
54 |
54 |
18.0 |
7.8 |
6.0 |
Day 13 |
7 |
3 |
52 |
53 |
92.0 |
3.9 |
0.0 |
Day 14 |
6 |
5 |
- |
- |
98.0 |
- |
- |
Day 21 |
- |
4 |
49 |
48 |
- |
11.8 |
12.0 |
Day 27 |
- |
5 |
48 |
45 |
- |
15.7 |
20.0 |
Day 28 |
- |
5 |
47 |
48 |
- |
17.6 |
14.0 |
Adsorption after 3 h in % mean |
1 |
Biodegradation after 28 d in % mean |
16 |
Total Elimination after 28 d in % mean |
17 |
*Negative values or values above 100 % are given as 0 % and 100 %, respectively.
Description of key information
FAT 20003 is not rapidly biodegradable, but fulfils the criteria of primary, inherent biodegradability.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, fulfilling specific criteria
- Type of water:
- freshwater
Additional information
Several studies evaluating the biodegradability of FAT 20003 are available, which included studies to determine the inherent biodegradability, as well as chemical oxygen demand (COD) and biological oxygen demand (BOD5).
BOD5/COD ratio:
The BOD5 and COD for FAT 20003/H were determined to be 0 and 572 mg/g O2 respectively, hence the BOD5/COD ratio was equal to 0.
The BOD5 and COD for FAT 20003/G were determined to be 53 and 1334 mg/g O2 respectively, hence the BOD5/COD ratio was equal to 0.04.
The BOD5 and COD for FAT 20003/F were determined to be 25 and 1014 mg/g O2 respectively, hence the BOD5/COD ratio was equal to 0.02.
The BOD5 and COD for FAT 20003/D were determined to be 170 and 1207 mg/g O2 respectively, hence the BOD5/COD ratio was equal to 0.14.
The BOD5/COD ratios in all above cases is <0.5, hence the substance should be considered as not rapidly biodegradable.
Inherent biodegradability:
In the key inherent biodegradability study (Zahn-Wellens/EMPA Test) with FAT 20003/I conducted according to OECD 302B, results indicated that Adsorption after 3 hours was 1 %, biodegradation after 28 days was 16 %, and total elimination after 22 days 17 %. Therefore, the test substance was determined to be non-biodegradable.
However, two other inherent biodegradability studies conducted with FAT 20003/H and FAT 20003/A indicated that the substance may fulfil the criteria for primary, inherent biodegradability by showing biodegradation 20 %.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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