Registration Dossier
Registration Dossier
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EC number: 251-257-2 | CAS number: 32846-21-2
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Identification: FAT 20003/K TE Lot. AT-0026132600
Appearance: Red powder - Key result
- Water solubility:
- 1 050 mg/L
- Temp.:
- 20 °C
- pH:
- 8.5
- Details on results:
- None
- Conclusions:
- The water solubility of the test item at a temperature of 20 °C was determined to be 1050 mg/L.
- Executive summary:
The water solubility of FAT 20003/K TE was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used fot this purpose. Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined to be 1050 mg/L.
Reference
Preliminary Visual Estimation of the Water Solubility
Appearance of the test mixtures in the preliminary test.
| Amount of the test item in mg | Total volume in ml | Appearance of mixture |
| 10 | 10 | Undissolved |
| 10 | 50 | Dissolved |
The preliminary visual experiments showed that the water solubility of the test item is >200 mg/l.
Flask-Method
Water solubility of the test item – experiments A to D.
Experiment |
A |
B |
C |
D(blank) |
Amount of test item(mg) |
1000 |
1000 |
1000 |
--- |
Stirring time at 30 °C (h) |
24 |
48 |
72 |
72 |
Extinction |
0.3600 |
0.3500 |
0.3800 |
0.0000 |
Measured Concentration(µg/ml) |
10.4 |
10.1 |
11.0 |
n.d. |
Aliquot |
0.1/10 |
0.1/10 |
0.1/10 |
0.1/10 |
Water solubility(mg/l) |
1040 |
1010 |
1100 |
--- |
Average experiments A to C: 1050 mg/l
Standard addition for recheck :
Standard |
Measured concentration (mg/l) |
% Recovery |
Sample C + 18.6 µg test item |
30.5 |
105.3 |
The recovery of 105.3 % indicates a sufficient accuracy of the analytical method.
Description of key information
The water solubility of FAT 20003/K TE was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used fot this purpose. Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined to be 1050 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 1 050 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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