Registration Dossier
Registration Dossier
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EC number: 601-730-8 | CAS number: 12065-65-5
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- Batch C000363565
- Key result
- Water solubility:
- 3.7 µg/L
- Conc. based on:
- element
- Remarks:
- Titanium
- Loading of aqueous phase:
- 300 g/L
- Incubation duration:
- 96 h
- Temp.:
- 20 °C
- pH:
- 5.7
- Key result
- Water solubility:
- 5.93 µg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 300 g/L
- Incubation duration:
- 96 h
- Temp.:
- 20 °C
- pH:
- 5.7
- Conclusions:
- According to OECD Test Guideline 105 (1995) and Regulation (EC) No 440/2008 Method A.6. the water solubility at 20 °C after 96 h stirring and a loading of 300 g/L of the test item Ti3O5/Al2O3 Granulat 0.7-5mm was determined to be 3.7 μg Ti/L, corresponding to 5.93 μg/L test item.
- Executive summary:
According to OECD Test Guideline 105 (1995) and Regulation (EC) No 440/2008 Method A.6. the water solubility at 20 °C after 96 h stirring and a loading of 300 g/L of the test item Ti3O5/Al2O3 Granulat 0.7-5mm was determined to be 3.7 μg Ti/L, corresponding to 5.93 μg/L test item.
Reference
At this point it should be noted that a very high loading (approx. 300 g/L) of the sample in the solvent water is used compared to a usual transformation dissolution screening test (100 mg/L, OECD series on testing and assessment number 29 (2001) Guidance document on transformation/dissolution of metals and metal compounds in aqueous media). This fact in connection with the result shows that the water solubility of the test item is very low.
Description of key information
According to OECD Test Guideline 105 (1995) and Regulation (EC) No 440/2008 Method A.6. the water solubility at 20 °C after 96 h stirring and a loading of 300 g/L of the test item Ti3O5/Al2O3 Granulat 0.7-5mm was determined to be 3.7 μg Ti/L, corresponding to 5.93 μg/L test item.
Key value for chemical safety assessment
- Water solubility:
- 5.93 µg/L
- at the temperature of:
- 20 °C
Additional information
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