Registration Dossier
Registration Dossier
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EC number: 220-168-0 | CAS number: 2650-18-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC 12, 20, 50, 80, 90 mg/L > 1000 mg/L
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
The following data were obtained for Similar Substance 1. It is expected that the Target substance will present similar effect levels to microorganisms. Justification for Read Across is given in Section 13 of IUCLID.
In a GLP guideline study according to OECD 209, the effects of the test item on micro-organisms from activated sludge by measuring oxygen consumption has been evaluated. After 3 h of exposure up to 1000 mg/kg, no effects on the respiration rate have been measured. Therefore, the EC10, EC20, EC50 and EC80 were determined to be > 1000 mg/L.
Additionally, the toxicity to microorganisms has been determined according DIN 38412 part 27 using Pseudomonas putida. After 30 min exposure the oxygen consumption has been measured. The EC10, EC50 and EC90 was determined to be above 10000 mg/L.
Therefore, the inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.
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