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EC number: 241-922-5 | CAS number: 18015-76-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Malachite Green Oxalate (MGO), hydrolysis t1/2 (45%) ca. 145h, dark conditions, ambient temperature
MG, t1/2, phototransformation in water, natural solar = 30h (8h irradiation/day); total phototransformation, 210h, 25°C
Additional information
Malachite Green (MG) does degrade due to hydrolysis with a measured approximate initial half-life of 145 hours at 25°C (45 % decrease in 145 hours, Perez et al, 2007).
The hydrolysis reaction was fit by first-order kinetics model and its apparent rate constant kh was 0.0192/h (R2 = 0.9409). Based on the structure of MG, the triarylmethyl cation is expected to be stabilized by the conjugation that delocalizes the positive charge and a good leaving group. Therefore, the hydrolysis mechanism should be SN1 mechanism and the reaction rate is unrelated to the concentration of the nucleophile H2O. The pH varied from 8.98 to 7.87 in the reaction process. Results from LC–MS conformed to the fact that MG, MG leucocarbinol and Leucomalachite Green can transform naturally to each other in water matrix (Yong et al, 2015).
Photolysis experiments (Perez et al, 2007) showed that total photolytic transformation of MG in the closed batch system occurred after 210 hours at a temperature of 25 °C. During this photolytic transformation of MG, it has been shown that a large number of transformation products were generated.
It has to be taken into account that the photolytic process is expected to be temperature- as well as wavelength-dependent and that the degradation rate can be differently impacted under sunlit natural waters with season (temperature) and depth (light intensity). It is expected that the photolysis rates decrease exponentially with depth and therefore the substance/degradation products distribution in a well-mixed waterbody would be mainly determined by the photolysis in the upper layer. The photodegradation importance in water strongly depends on the light shadow of the water constituents. It has to be taken into account that also the presence of suspended solids or sediments in natural waters may impact on the photoreactivity of the test substance reducing the availability of light; in suspensions containing large amounts of particles the presence of particles may lead to a shift in the photostationary state of the substance.
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