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Diss Factsheets
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EC number: 204-699-5 | CAS number: 124-41-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil microorganisms
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
Key value for chemical safety assessment
Additional information
In contact with water, sodium methanolate rapidly hydrolyses to methanol and sodium hydroxide (OECD, 2002). Thus, the degradation products of sodium methanolate are of relevance for the assessment of environmental toxicity.
No studies on the toxicity to soil microorganisms are available for sodium methanolate or the degradation products methanol and sodium hydroxide. All available data on terrestrial organisms as well as activated sludge microorganisms do not indicate a need to investigate the effects of the substance and relevant degradation products on soil microorganisms.
Sodium hydroxide
Sodium hydroxide further dissociates in the environment
to sodium (K+) and hydroxyl ions (OH-). Sodium belongs to the alkali
metals and is one of the most common elements in the earth crust.
Together with potassium ions (K+), sodium ions (Na+) are responsible for
maintaining the cell membrane potential and essential for the function
of all living cells (Clausen&Poulsen, 2013). Many physiological
processes in organisms are driven by the influence of sodium. Thus,
sodium ions are not considered to be relevant for aquatic toxicity.
Hydroxyl ions may cause a change (increase) of pH of the receiving
environmental compartment. This may result in effects on aquatic
organisms in case the pH is changed outside of the tolerable pH-range.
Thus, hydroxyl ions do not have an intrinsic toxicity but may cause
physical effects depending on the buffer capacity of the aqueous medium
(OECD, 2002). It has to be noted that effluents from sewage treatment
plants are measured frequently for its pH and are appropriately adapted
before release if needed. In addition, due to the dilution effects and
buffer capacity of natural aquatic ecosystems significant pH changes
followed by effects on aquatic species are not expected (OECD, 2002). In
conclusion, any observed effects after exposure of terrestrial organisms
to sodium hydroxide is considered to be solely caused by a potential
change of pH. Sodium ions are not considered to contribute to
terrestrial toxicity.
Methanol
Data on methanol investigating the long-term toxicity
to soil organisms are available for terrestrial plants, earthworms and
terrestrial arthropods (Stantec 2006).
All available studies indicate a low toxicity of methanol to terrestrial organisms with NOEC values≥1000 mg/kg.
Thus, no further testing on soil microorganisms is deemed necessary for sodium methanolate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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