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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test method according to OECD TG 301 C. No data on GLP. .
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 301 C(Ready Biodegradability: Modified MITI Test (I))
GLP compliance:
not specified
Analytical monitoring:
yes
Vehicle:
not specified
Test organisms (species):
activated sludge
Details on inoculum:
- Initial biomass concentration: 30 mg/L
Test type:
other: Readily biodegradability
Water media type:
freshwater
Limit test:
no
Total exposure duration:
28 d
Details on test conditions:
TEST SYSTEM
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): BOD and test item concentration by HPLC.

TEST CONCENTRATIONS
- Test concentrations: 100 mg/L.
Reference substance (positive control):
not specified
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: % biodegradability

The test item was determined not to be toxic in the biodegradability test although not been readily biodegradable.

Validity criteria fulfilled:
not specified
Conclusions:
The NOEC for microorganism toxicity of the test item was determined to be 100 mg/L.
Executive summary:

A readily biodegradation test was performed on 2 -methylcyclohexyl acetate by MITI according to OECD Guideline 301 C. 30 mg/L of activated sludge were exposed to 100 mg/L test item for 4 weeks. The biodegradation obtained by indirect analysis was 0 (basis for effect: BOD), and by direct analysis 2% (basis for effect: HPLC). The test item was deterined not to be toxic under test conditions. According to the current guidelines, the NOEC for microorganism toxicity was determined to be 100 mg/L.

Description of key information

Key study: OECD 301C. No data on GLP. The NOEC for microorganism toxicity was determined to be 100 mg/L.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
100 mg/L

Additional information

Key study: Experimental results:

A readily biodegradation test was performed on test item by MITI according to OECD Guideline 301 C. The NOEC for microorganism toxicity was determined to be 100 mg/L.