Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-159-0 | CAS number: 78-93-3
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- secondary source
- Title:
- No information
- Bibliographic source:
- ECHA database; http://apps.echa.europa.eu/registered/data/dossiers/DISS-9d91195a-65f3-618d-e044-00144f67d249/DISS-9d91195a-65f3-618d-e044-00144f67d249_DISS-9d91195a-65f3-618d-e044-00144f67d249.html
Materials and methods
- Study type:
- other: General description of symptoms and effects seen in workers exposed to butanone vapours
Results and discussion
- Clinical signs:
- Air analyses revealed concentration of butanone from 300 to 600 ppm.
Workers developed disabling dermatoses and several workers complained of numbness of the fingers and arms.
One worker described one shoulder ‘as though it was made of dough and did not belong to him’ so that he could not lie on it at night.
Another worker complained of numbness in the legs and a tendency for them to suddenly give way under him.
Two men who merely worked in the rooms where the solvent was present in the air but had no occasion to touch it developed dermatitis which originated on the face and was confined to that area.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
