Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 465-100-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
Test material
- Test material form:
- solid: particulate/powder
- Details on test material:
- Batch number: 022401
Constituent 1
- Specific details on test material used for the study:
- Purity: 79.8 %
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- Activated sludge was collected from a sewage treatment works A-2500 Baden, which waste water catchment is predominantly domestic. On arrival in the laboratory, the sample was aerated by means of a filtered compressed air before being used for the study.
- Duration of test (contact time):
- ca. 28 d
Initial test substance concentration
- Initial conc.:
- ca. 55 mg/L
- Based on:
- ThCO2
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- 2400 ml mineral medium were added to each of 5-litre flask. The test substance was suspended in the medium which was free of CO2 by purging with CO2 free air, at a concentration of nominally 15 mg organic carbon per litre. The reference substance was added for groups PK and TK (15 mg organic carbon/L.). Each vessel was inoculated with micro-organisms derived from a sample of activated ludge and was filled up to a total volume of 3000 ml. The vessels were incubated in darkness until the end of the study and the medium continually supplied with CO2-free air. Barium hydroxide was used to trap the CO2 formed by the degradation of the test substance. Three absorption bottles were connected in line each containing 100 ml of 0.0125 M barium hydroxide solution, in series to each 5-litre flask. On the days of CO2 measurement, the barium hydroxide absorbers closest to the test vessels were disconnected and the barium-hydroxide solution was titrated with 0.05 M HCI using phenolphthalein as the indicator. The remaining absorbers were connected to the incubation vessels and a new absorber containing 100 ml fresh 0.0125 M barium hydroxide was placed at the far end of the series. In case a substantial precipitation was seen in the first trap, also the second bottle was analysed.
The incubation was conducted in a facility where the temperature was controlled to be within the range of 22 ± 2 °C.
Determinations were performed of samples of blank and positive control vessels at the beginning of the test. The reason for omitting the vessels which contained the test substance was the risk to remove relevant amounts of the test substance when withdrawing the possibly coated pH electrode.
The air flow was regulated for each vessel individually. Air flow was determinated volumetrically in intervals. Adjustments were made as necessary to maintain a flow rate in the range 50 to 100 ml per minute. The air used was a COrfree "control air" (Linde Gase, A-2492 Eggendorf). As an added precaution, a 0.0125 M b:trium hydroxide solution was used as CO2 absorber.
Reference substance
- Reference substance:
- other: sodium benzoate
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 9.6
- Sampling time:
- 28 d
- Details on results:
- Points of degradation plot (test substance):
9 % degradation after 10 d
9.7 % degradation after 20 d
9.6 % degradation after 28 d
BOD5 / COD results
- Results with reference substance:
- Points of degradation plot (reference substance):
63.4 % degradation after 10 d
72.4 % degradation after 20 d
76.4 % degradation after 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- The satisfactory response recorded for the reference substance indicates that the failure of "STl571 F8" to degrade extensively in this study cannot be attributed to the deficiencies of either the test method or the inoculum.
- Interpretation of results:
- not readily biodegradable
- Remarks:
- "STl571 F8" is not readily biodegradable as the biodegradation reached only 9.6 % after 28 days.
- Conclusions:
- "STl571 F8" is not readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Deși ECHA oferă o varietate bogată de materiale online în limba dumneavoastră, o parte din conţinutul acestei pagini este disponibil numai în limba engleză. Pentru mai multe informaţii referitoare la practica multilingvă a ECHA.
Bun venit pe site-ul ECHA. Acest site nu este deplin acceptat în Internet Explorer 7 (și versiuni anterioare). Vă rugăm să vă actualizați versiunea de Internet Explorer.
Acest site folosește module cookie pentru a garanta că aveți parte de cea mai bună experiență pe paginile noastre.
Aflați mai multe despre cum folosim modulele cookie.