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Diss Factsheets
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EC number: 419-560-6 | CAS number: 4369-14-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- according to guideline
- Guideline:
- other: Japanese guidelines for testing of chemicals “Ready biodegradability of chemical substance by microbe”
- GLP compliance:
- yes
- Oxygen conditions:
- not specified
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- > 0 - <= 28 d
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- No details available
- Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- 26
- Sampling time:
- 7 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 41
- Sampling time:
- 28 d
- Details on results:
- No details available.
- Key result
- Parameter:
- BOD5
- Value:
- ca. 0.67 g O2/g test mat.
- Key result
- Parameter:
- COD
- Value:
- 1.64 g O2/g test mat.
- Results with reference substance:
- The reference substance attained 71% degradation by study day 7.
- Validity criteria fulfilled:
- yes
- Remarks:
- Based on the limited information available
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The biodegradation rate of the substance was determined to be 41% after 28-day exposure to sludge. However, this was due to the complete biodegradation of the methanol hydrolysis product. Therefore, the substance was classified as 'not readily biodegradable'.
Reference
Inhibition of microbial activity
Comments: The biodegradation rate of the material was 41% after 28-day exposure to sludge. It was fully determined by chemical analysis that the 41% could be attributed to the complete biodegradation of methanol, produced from hydrolysis of the material.
This result indicates that the material has no inhibitory effect to any bacteria in biodegradation procedure.
Ready biodegradability
Degradation: 41%
Classification: not readily biodegradable
Reference substance: aniline
Experimental values:
Test substance |
Reference substance |
||
Day |
Percentage % |
Day |
Percentage % |
7 |
26 |
7 |
71 |
28 |
41 |
28 |
75 |
See attachment for degradation curve.
Biological oxygen demand
Biological oxygen demand measured over 5 days = 0.67 g O2/g (BOD) at 28 day exposure.
Chemical oxygen demand = 1.64 g O2/g (COD)
BOD/COD = 41%
Comments: It was demonstrated by chemical analysis that the BOD value was due to the biodegradation of methanol produced by the hydrolysis of the substance.
Description of key information
Biodegradation in water, screening tests: 41% in 28 days (O2 consumption). The silanol hydrolysis product, 3-acryloxypropylsilanetriol, is not expected to biodegrade to any significant extent.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
A biodegradation of 41% in 28 days (O2 consumption) was determined in a reliable study conducted according to an appropriate test protocol, and in compliance with GLP.
In contact with water, the submission substance hydrolyses rapidly to form 3-acryloxypropylsilanetriol and methanol. Hydrolysis of the parent submission substance is expected to be significant during the cause of the biodegradation study. Therefore, the biodegradation observed is expected to be as a result of the methanol hydrolysis product.
No significant biodegradation is expected for the silanol hydrolysis product; 3-acryloxypropylsilanetriol.
Methanol is readily biodegradable (OECD 2004).
Reference:
OECD (2004): SIDS Initial Assessment Report for SIAM 19, Berlin, Germany, 18-20 October 2004, Methanol, CAS 67-56-1.
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