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EC number: 244-543-3 | CAS number: 21722-83-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-cyclohexylethyl acetate
- EC Number:
- 244-543-3
- EC Name:
- 2-cyclohexylethyl acetate
- Cas Number:
- 21722-83-8
- Molecular formula:
- C10H18O2
- IUPAC Name:
- 2-cyclohexylethyl acetate
Constituent 1
- Specific details on test material used for the study:
- 6.1 Test Item
Designation in Test Facility: 17112908G
Date of Receipt: 29. Nov. 2017
Condition at Receipt: Room temperature, in proper conditions
6.1.1 Specification
The following information concerning identity and composition of the test item was provid-ed by the sponsor.
Name Cyclohexyl ethyl acetate
Batch no. CP014-171101
Appearance colorless and transparent liquid
Composition Cyclohexyl ethyl acetate
CAS No. 21722-83-8
EINECS-No. 244-543-3
Molecular formula C10H18O2
Molecular weight 170.25 g/mol
Purity 99.85 %
Homogeneity homogeneous
Vapour pressure unknown
Stability in solvents unknown
Solubility in solvents unknown
Production date 01. Nov. 2017
Expiry date 30. May 2019
Storage Room Temperature (20 ± 5 °C)
6.1.2 Storage in Test Facility
The test item was stored in a tightly closed vessel at room temperature (20 ± 5 °C).
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Activated sludge from a biologic sewage treatment plant was used. The chosen plant is treating mostly household sewage.
The sludge was taken from the activation basin of the sewage treatment plant, In den Seewiesen, 67435 Edenkoben.
Date of collection: 09. May 2018, batch no:20180509.
The sludge was filtrated, washed with medium 2x, and re-suspended in test medium. It was then aerated.
The dry matter was determined as 3880mg suspended solids/L. - Duration of test (contact time):
- ca. 28 d
Initial test substance concentration
- Initial conc.:
- ca. 39 mg/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- benzoic acid, sodium salt
- Remarks:
- positive control
Results and discussion
- Test performance:
- All validity criteria were met.
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 55
- Sampling time:
- 10 d
- Remarks on result:
- other: When applying the 10-day-window, the test item Cyclohexyl ethyl acetate is not readily biodegradable following OECD 301F/EU C.4-D.
- Details on results:
- All validity criteria were met.
Oxygen consumption in the blank controls and in the positive controls was normal, indicating that the test system has worked properly.
As a plateau of degradation was reached it is considerable, that the maximal degradation of the test item due to the test conditions was reached.
The ThOD of the test item was calculated and based on molecular formula of the test item, given by the sponsor. The 10-day-window began on day 1 (this is stated as lag phase), at its end (day 11), 55 % were reached, missing the pass level of 60 % given in the OECD guideline.
As a plateau of degradation was reached it is considerable, that the maximal degradation of the test item due to the test conditions was reached.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Therefore, when applying the 10-day-window, the test item Cyclohexyl ethyl acetate is considered as not readily biodegradable following OECD 301F/EU C.4-D.
As degradation surpassed 60 % in the course of the test, Cyclohexyl ethyl acetate is con-sidered as ultimately biodegradable, within 28 days.
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