Registration Dossier
Registration Dossier
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EC number: 206-126-4 | CAS number: 302-72-7
Endpoint summary
Administrative data
Description of key information
DL-alanine was observed to be readily biodegradable by Weltens (2018). In line with the expectations was L-alanine also found to be readily biodegradable.
Additional information
The ready biodegradability of DL-Alanine in water under aerobic conditions was determined according to OECD Guideline 301B (1992) - CO2-evolution test and in compliance with GLP criteria.
The amount of test and reference item added to the test vessels represented 20 mg/L C.
The inoculum (active sludge) was collected at a domestic wastewater treatment plant (City of Geel, Aquafin station). The sludge was washed and kept in the lab in low carbon conditions during 6 days. In the test vessels, 30 mg/L DW was used. The temperature was set to 19.5 - 22.0°C at diffuse light conditions.
The CO2produced in the test vessels was trapped in a 0.05 N NaOH solution. Samples were taken from the NaOH traps every 2-3 days for inorganic carbon (IC) measurements. The duration of the test was 20 days (started on 15/02/2018 - ended on 7/03/2018). All validity criteria were met.
The 10-days window started on day 4. The pass level (60% of ThCO2) was reached on day 11 and the plateau value (around 75% of ThCO2) was reached on day 16.
Based on these results DL-Alanine is considered ready biodegradable.
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