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EC number: 249-616-3 | CAS number: 29420-49-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water: sewage treatment simulation testing
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2008
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Study is of the free acid form of PFBS. In buffered solution, biodegradation testing on the acid is equivalent to testing on the potassium salt.
Data source
Reference
- Reference Type:
- publication
- Title:
- Degradation Studies of New Substitutes for Perfluorinated Surfactants
- Author:
- Quinete N, Orata F, Maes A, Gehron M, Bauer KH, Moreira I, Wilken RD
- Year:
- 2 010
- Bibliographic source:
- Arch Environ Contam Toxicol 59(1): 20-30; DOI 10.1007/s00244-009-9451-3
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- - Principle of test: Fixed Bed Bioreactor system
- Short description of test conditions: Continuous flow-through at room temperature, neutral pH in darkness
- Parameters analysed / observed: primary biodegradation - GLP compliance:
- no
Test material
- Reference substance name:
- 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic acid
- EC Number:
- 206-793-1
- EC Name:
- 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic acid
- Cas Number:
- 375-73-5
- Molecular formula:
- C4HF9O3S
- IUPAC Name:
- 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonic acid
Constituent 1
- Specific details on test material used for the study:
- PFBS standard (98%) was obtained from Sigma–Aldrich (Germany)
- Radiolabelling:
- no
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- natural water: freshwater
- Details on source and properties of surface water:
- - Details on collection: Details of the inoculum are unclear. The paper describes the inoculum as being Rhine River water. It is presumed that the same sample, from km 463.6 near Biebesheim, was used as for a parallel closed bottle test. The water was recirculated at a flow rate of 16 mL/min through a glass column packed to 18 cm depth with glass beads to allow a biofilm to develop. The duration of biofilm development was not stated. The experiment was done with water from a pristine creek near Biebesheim, 5 L total volume. Aeration was provided by a membrane pump within the water reservoir. The experiment was run for 28 days .
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- test mat. analysis
Results and discussion
% Degradation
- Key result
- Remarks on result:
- other: No significant degradation, relative standard deviation of peak area ≤7%
- Results with reference substance:
- No reference substance was reported, however a second fluorinated surfactant tested in parallel showed ≥60% biodegradation within 28 days. This demonstrates biological efficacy of the developed bioreactor.
Applicant's summary and conclusion
Validity criteria
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- PFBS was not biodegraded in a bioreactor system using a river water inoculum under neutral, aerobic conditions. Results are directly applicable to PFBSK+
- Executive summary:
PFBS biodegradation was examined in a fixed-bed bioreacter using a river water source. River water was recirculated in a glass bead-packed column to allow a biofilm to develop. PFBS was recirculated for 28-days under aerobic conditions, at room temperature with neutral pH in darkness. Samples were taken weekly and analyzed by HPLC/MS/MS. A second fluorinated surfactant was examined in a parallel study. PFBS was not measurably biodegraded (RSD of HPLC peak areas ≤7%) over the test interval, whereas the other surfactant was degraded >60% at the same time. PFBS is not ultimately biodegradable. In neutral media, biodegradation testing on the free acid is equivalent to testing on the salt. Therefore, results for PFBS are directly applicable to PFBSK+.
The test was conducted using scientifically valid methods with a suitable level of detail, and results indicated the ability of the system to detect degradation of another, less-recalcitrant material. The results are considered reliable with restrictions and suitable for Risk Assessment, Classification & Labelling, and PBT analysis.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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