Registration Dossier
Registration Dossier
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EC number: 289-124-6 | CAS number: 86014-76-8
Endpoint summary
Administrative data
Description of key information
Additional information
A read-across approach was followed in order to obtain the information regarding aquatic toxicity. Ecotoxicological data are available for two different trophic levels by testing Daphnia magna (invertebrates) and Scenedesmus subspicatus (algae).
From the avaiable studies, Daphnia was identified as the most sensitive organism, with an EC50 (48 h) of 1.03 mg/l. Algae showed an IC50 (72 h) value of 3.4 mg/l.
The bioaccumulation potential could be excluded due to the very low logKow and high molecular weight, which limits the ability of the substance to cross biological membranes.
Conclusion on classification
In the light of a cautelative worst-case approach, the experimental data of the Similar Substance 01 was used for classification under CLP Regulation (EC 1272/2008).
Acute aquatic hazard
According to the Regulation EC 1272/2008 (CLP), the substance does not meet the criteria for classificiation as Environmental Acute Toxicity since neither the EC50 values for invertebrates nor algae are below or equal to 1 mg/l.
Chronic aquatic hazard
Adequate chronic toxicity data are not available for the substance, and the substance is not rapidly biodegradable thus the classification for long-term aquatic hazard will be based on the acute data available.
From the avaiable studies, Daphnia was identified as the most sensitive organism, with an EC50 (48 h) value of 1.03 mg/l. Algae showed an IC50 (72 h) value of 3.4 mg/l.
In conclusion, according to the CLP Regulation EC n. 1272/2008, the substance does meet the criteria for classification as Aquatic Chronic 2 since, based on the available data, the L/EC50 values of either fish, crustacea or algae are within the 1 - 10 mg/l range and the substance is not readily biodegradable.
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