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EC number: 701-480-0 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Test data is available on the acute toxicity of copper slag to invertebrates. Lowest short-term toxicity value observed is greater than 100 mg/l or >10 to < or equal 100 mg/l
Key value for chemical safety assessment
Additional information
A GLP OECD 202 guideline study (Simon, 2011) was performed which assessed the effect of mesocosm water extracts of five slags on the immobilization of Daphnia magna. The 48 h EC50 for copper slag in the range of 980 mg/l to >6250 mg/l were found. Typical slag samples have been tested which were within the composition concentration range defined in IUCLID Section 1.2.
Further OECD 202 guideline studies (Lebertz, 2007) and (Sauerwald and Weiss, 2004) investigated the toxicity of copper slag on Daphnia magna in a 48h limit test. No toxic effects were observed at tested concentrations. EC50 and EC10 values of >1000 mg/L and > 100 g/l respectively were assessed. Typical slag samples have been tested which were within the composition concentration range defined in IUCLID Section 1.2.
The calculated classification via Toxic unit approach (MeClas) resulted in "Acute Category 3" classification for the UVCB substance. Based on this result, the related criteria provided the estimated value for acute (short term) toxicity to aquatic invertebrate (see EU CLP Annex I Table 4.1.0): 48hr EC50 (for crustacea) >10 to < or equal 100 mg/l
Using a weight of evidence approach, the lowest short-term toxicity of copper slag to invertebrates is greater than 100 mg/l or >10 to < or equal 100 mg/l which means No classification or Acute 3 classification.
The following information is taken into account for the derivation of PNEC:
The 48 h EC50 for Daphnia magnain the range of 980mg/l to >6250 mg/l obtained in the GLP bridging study (Simon, 2011)
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