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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: not under GLP, well documented, basic data given

Data source

Reference
Reference Type:
other: Investigation Report Chemical Property - DCP
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloro-1-(4-chlorophenyl)propan-1-one
EC Number:
810-506-0
Cas Number:
877-38-3
Molecular formula:
C9H8Cl2O
IUPAC Name:
2-chloro-1-(4-chlorophenyl)propan-1-one
Constituent 2
Reference substance name:
2,4'-dichloropropiophenone
IUPAC Name:
2,4'-dichloropropiophenone
Test material form:
other: white or yellowish white solid

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
isopropanol
Solubility:
89 g/L
Remarks on result:
other: ambient temperature
Medium:
acetone
Solubility:
2 328 g/L
Remarks on result:
other: ambient temperaure
Medium:
other: MTBE
Solubility:
947 g/L
Remarks on result:
other: ambient temperature
Medium:
methanol
Solubility:
347 g/L
Remarks on result:
other: ambient temperaure
Medium:
dimethylformamide
Solubility:
1 730 g/L
Remarks on result:
other: ambient temperautre

Applicant's summary and conclusion

Executive summary:

The solubility of 2,4'-dichloropropiophenone in five different organic solvents was reported in the document "Investigation Report Chemical property - DCP from Höfner (2015). The highest value of the solubility was reached in acetone. The study on the solubility in organic solvents is considered to be reliable with restrictions.