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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: not under GLP, well documented, basic data given

Data source

Reference
Reference Type:
other: Investigation Report Chemical Property - DCP
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Test material form:
other: white or yellowish white solid

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
isopropanol
Solubility:
89 g/L
Remarks on result:
other: ambient temperature
Medium:
acetone
Solubility:
2 328 g/L
Remarks on result:
other: ambient temperaure
Medium:
other: MTBE
Solubility:
947 g/L
Remarks on result:
other: ambient temperature
Medium:
methanol
Solubility:
347 g/L
Remarks on result:
other: ambient temperaure
Medium:
dimethylformamide
Solubility:
1 730 g/L
Remarks on result:
other: ambient temperautre

Applicant's summary and conclusion

Executive summary:

The solubility of 2,4'-dichloropropiophenone in five different organic solvents was reported in the document "Investigation Report Chemical property - DCP from Höfner (2015). The highest value of the solubility was reached in acetone. The study on the solubility in organic solvents is considered to be reliable with restrictions.