Registration Dossier
Registration Dossier
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EC number: 201-837-6 | CAS number: 88-51-7
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: international guideline to the safe transportation or shipment of dangerous goods or hazardous materials by water on vessel
Data source
Reference
- Reference Type:
- publication
- Title:
- OECD SIDS 4-aminotoluene-3-sulfonic acid
- Author:
- UNEP Publications
- Year:
- 2 003
Materials and methods
- Principles of method if other than guideline:
- Method: other: IMDG code (2002)
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-aminotoluene-3-sulphonic acid
- EC Number:
- 201-831-3
- EC Name:
- 4-aminotoluene-3-sulphonic acid
- Cas Number:
- 88-44-8
- Molecular formula:
- C7H9NO3S
- IUPAC Name:
- 2-amino-5-methylbenzenesulfonic acid
- Details on test material:
- Mitsuboshi Chemical Co., Ltd.: purity >99%
Constituent 1
Test animals
- Species:
- human
Test system
- Type of coverage:
- occlusive
- Preparation of test site:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Controls:
- no
- Amount / concentration applied:
- ca. 50 mg/patch applied on an inner arm.
- Duration of treatment / exposure:
- 6 hours
- Observation period:
- 14 days
- Number of animals:
- Five male humans aged between 27 and 48 years.
Results and discussion
In vivo
- Irritant / corrosive response data:
- No signs of irritation were reported.
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information
- Conclusions:
- Not irritating
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