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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
27th February 2013 - 27th June 2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted according OECD and EC Test Guidelines in a GLP accredited lab
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
> 6.2
Temp.:
25 °C
pH:
4
Remarks on result:
other: The test was conducted at pH 4 in order to examine the test substance in its non-ionised form
Details on results:
The first eluting peak at 1.4 minutes in the standard and sample chromatograms was the internal deadtime standard, formamide. It was evident that all components of the reference mixture eluted earlier than T-1620L under the test conditions, with the last standard (DDT, known log10Pow = 6.2) eluting after 4.8 minutes. A value of log10Pow for T-1620L of greater than 6.2 was thus obtained.
Conclusions:
T-1620L was found to have a log10Pow value of greater than 6.2.

Description of key information

T-1620L was found to have a log10Pow value of greater than 6.2.

Key value for chemical safety assessment

Additional information