4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: According to guideline OECD 105

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

4-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzene-1-sulfonic acid

EC Number:

201-901-3

Cas Number:

89-36-1

Molecular formula:

C10H10N2O4S

IUPAC Name:

4-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzene-1-sulfonic acid

Results and discussion

Water solubility

Water solubility:

5.16 g/L

Temp.:

20 °C

pH:

1.9

Remarks on result:

other: mean of 3 measurements

Any other information on results incl. tables

Flask No.	Equilibration time at 20 °C [h]	pH of aqueous solution	Test substance content [g/L]
1	24	1.9	5.27
2	48	1.9	5.11
3	72	1.9	5.12
mean	---	---	5.16

Applicant's summary and conclusion

Conclusions:

Interpretation of results (migrated information): soluble (1000-10000 mg/L)

Executive summary:

The water solubility was determined according to OECD TG 105. After a preliminary test, the shake flask method was chosen and yielded a water solubility of 5.16 g/L at 20 °C.