Registration Dossier
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EC number: 232-019-7 | CAS number: 7783-66-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of iodine pentafluoride to algae is derived from experimental data with its degradation products iodide, iodate and fluoride. As no data with iodate and iodide are available for this endpoint, an experimental study with iodine is assessed. In this study an EC50 of 0.13 mg/L and a NOEC of 0.025 mg/L were determined. After correction for molecular weight, the EC50 and NOEC values for iodate are 0.09 mg/L and 0.017 mg/L, respectively. For iodide correction for molecular weight gives EC50 and NOEC values of 0.065 mg/L and 0.0125 mg/L, respectively.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.065 mg/L
- EC10 or NOEC for freshwater algae:
- 0.013 mg/L
Additional information
No aquatic toxicity studies with iodine pentafluoride are available or can be performed as in contact with water iodine pentafluoride reacts instantly and violently under formation of hydrogen fluoride and iodate. Hydrogen fluoride will further react to fluoride and iodate in water forms an equilibrium with iodide. Therefore available data from studies with fluoride, iodate and iodide are given as indication of the aquatic toxicity of iodine pentafluoride. As no data on iodate and iodide is available, read across is made to the aquatic toxicity data of iodine (I2).
A GLP-compliant OECD guideline 201 study is available for iodine (Harlan, 2010). In this study the aquatic toxicity of iodine to algae (Desmodesmus subspicatus) was investigated. The 72 hour EC50 for growth rate was 0.13 mg/L and the NOEC for growth rate was 0.025 mg/L. These values will be used for risk assessment.
In the EU Risk Assessment Report for hydrogen fluoride two studies with freshwater alga are reported (EU-RAR, 2001). Both reported tests were performed with sodium fluoride and the results corrected for the fluoride ion. Although data on test conditions are not available, as the data have been reviewed by the EU, these data are considered to be suitably reliable for environmental risk assessment. The lowest effect-value was observed in Scenedesmus sp. with a 96 -h EC50 for biomass of 43 mg fluoride/L.
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