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EC number: 700-789-8 | CAS number: 14352-61-5
Table 1 Body weight and weight gain in grams of the six female rats subjected to the test substance at a dose of 2,000mg/kg bw.
Dx (x=0,2,7,14) stands for the number of days after the administration of the test substance.
The acute toxicity class method (OECD 423 (2001)) was used to assess the acute toxicity of test substance in 6 female Sprague-Dawley rats.
The test substance was administered by oral gavage to the rats at a dose level of 2,000 mg/kg body weight. Animals were observed daily and their body weights were weekly recorded. Macroscopic examination was performed after sacrifice.
One mortality occurred on day 1. The other animals recovered normal behaviour within 24h.
The body weight gain was normal.
No abnormalities were found at post mortem macroscopical examinations of the animals.
The LD50 of the test substance exceeds 2,000 mg/kg body weight. Based on the result, the LD50 cut-off value is 2,500 mg/kg body weight.
Consequently, the test substance does not need to be classified according to Regulation EC No. 1272/2008.
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